| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 92 | 32 | 32 | 12 | 12 | 4.54 | .302 | 1.29 | 8.9 | 2.7 | 7.4 | 206.1 | 204 | 113 | 104 | 16 | 62 | 169 | 2 | 0 | 0 | 1 | 18 | 2 | 3 | 3.30 |
| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 94 | 32 | 32 | 16 | 8 | 4.02 | .305 | 1.29 | 8.6 | 3.0 | 6.2 | 214.2 | 205 | 101 | 96 | 21 | 72 | 148 | 1 | 0 | 0 | 0 | 18 | 5 | 1 | 3.97 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 32 | 32 | 12 | 13 | 5.98 | .336 | 1.50 | 10.6 | 2.9 | 8.3 | 173.0 | 203 | 125 | 115 | 23 | 56 | 160 | 0 | 0 | 0 | 0 | 13 | 4 | 11 | 3.92 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 29 | 29 | 6 | 16 | 5.34 | .335 | 1.47 | 10.7 | 2.6 | 3.6 | 141.2 | 168 | 95 | 84 | 13 | 40 | 56 | 0 | 0 | 0 | 0 | 10 | 6 | 2 | 4.38 |
| CL | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 94 | 57 | 0 | 5 | 5 | 3.25 | .341 | 1.55 | 5.7 | 8.3 | 11.3 | 55.1 | 35 | 21 | 20 | 3 | 51 | 69 | 0 | 32 | 7 | 0 | 0 | 0 | 4 | 3.98 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 75 | 0 | 5 | 4 | 3.87 | .299 | 1.26 | 8.6 | 2.8 | 8.9 | 90.2 | 86 | 39 | 39 | 18 | 28 | 89 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 4.62 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 63 | 0 | 3 | 2 | 5.28 | .336 | 1.47 | 8.3 | 5.0 | 9.0 | 61.1 | 56 | 37 | 36 | 6 | 34 | 61 | 0 | 1 | 1 | 0 | 0 | 3 | 2 | 4.10 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 39 | 0 | 6 | 1 | 4.68 | .372 | 1.71 | 10.7 | 5.1 | 6.5 | 32.2 | 38 | 19 | 17 | 5 | 18 | 23 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 5.47 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 18 | 0 | 3 | 1 | 4.82 | .341 | 1.50 | 9.5 | 4.5 | 8.5 | 18.2 | 19 | 10 | 10 | 1 | 9 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.50 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 25 | 0 | 1 | 0 | 4.55 | .346 | 1.55 | 9.7 | 4.7 | 8.3 | 27.2 | 29 | 15 | 14 | 5 | 14 | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.22 |