| SP | McNally, D.McNally, Dave † >> | 26 | 1968 | L | 96 | 33 | 33 | 19 | 9 | 3.42 | .282 | 1.16 | 8.0 | 2.5 | 5.7 | 245.0 | 217 | 96 | 93 | 18 | 68 | 154 | 11 | 0 | 0 | 2 | 19 | 4 | 6 | 3.58 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 34 | 34 | 16 | 16 | 4.07 | .298 | 1.26 | 8.8 | 2.6 | 4.6 | 261.0 | 254 | 129 | 118 | 26 | 75 | 133 | 16 | 0 | 0 | 1 | 20 | 4 | 4 | 4.18 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 33 | 33 | 11 | 13 | 4.64 | .297 | 1.25 | 7.6 | 3.7 | 4.7 | 230.2 | 193 | 127 | 119 | 30 | 95 | 121 | 9 | 0 | 0 | 0 | 12 | 5 | 3 | 4.95 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 31 | 31 | 12 | 10 | 4.34 | .328 | 1.45 | 9.2 | 3.9 | 4.7 | 184.2 | 188 | 98 | 89 | 20 | 79 | 97 | 1 | 0 | 0 | 0 | 14 | 3 | 3 | 4.70 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 73 | 0 | 5 | 4 | 3.19 | .290 | 1.22 | 7.9 | 3.1 | 7.8 | 98.2 | 86 | 38 | 35 | 4 | 34 | 85 | 0 | 10 | 3 | 0 | 0 | 1 | 0 | 2.87 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 62 | 0 | 1 | 5 | 4.91 | .328 | 1.45 | 9.3 | 3.9 | 9.7 | 69.2 | 71 | 39 | 38 | 10 | 30 | 74 | 0 | 8 | 3 | 0 | 0 | 1 | 3 | 4.09 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 50 | 0 | 6 | 3 | 2.86 | .273 | 1.11 | 6.7 | 3.3 | 7.9 | 63.0 | 47 | 23 | 20 | 7 | 23 | 55 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 3.84 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 2 | 2 | 0 | 1 | 3.52 | .343 | 1.50 | 10.2 | 3.6 | 7.2 | 15.1 | 17 | 6 | 6 | 1 | 6 | 12 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 3.67 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 2 | 0 | 0 | 0 | 0.00 | .200 | 0.75 | 4.5 | 4.5 | 9.0 | 2.2 | 1 | 0 | 0 | 0 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.50 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 22 | 0 | 2 | 4 | 5.45 | .349 | 1.61 | 10.4 | 4.0 | 3.8 | 38.0 | 44 | 27 | 23 | 4 | 17 | 16 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.87 |