| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 33 | 33 | 11 | 12 | 3.98 | .300 | 1.27 | 8.8 | 2.7 | 8.4 | 212.2 | 207 | 98 | 94 | 24 | 64 | 197 | 1 | 0 | 0 | 0 | 24 | 2 | 4 | 3.55 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 32 | 32 | 11 | 10 | 4.33 | .317 | 1.36 | 9.4 | 2.8 | 5.8 | 210.0 | 219 | 104 | 101 | 14 | 66 | 136 | 3 | 0 | 0 | 0 | 18 | 7 | 5 | 3.61 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 32 | 32 | 9 | 13 | 5.59 | .329 | 1.44 | 9.7 | 3.3 | 5.0 | 207.2 | 224 | 136 | 129 | 27 | 76 | 115 | 4 | 0 | 0 | 1 | 13 | 5 | 5 | 4.76 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 32 | 32 | 7 | 17 | 5.50 | .337 | 1.49 | 10.1 | 3.3 | 8.5 | 196.1 | 221 | 131 | 120 | 32 | 71 | 186 | 2 | 0 | 0 | 0 | 9 | 8 | 4 | 4.43 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 31 | 30 | 8 | 14 | 5.87 | .346 | 1.55 | 9.6 | 4.4 | 7.8 | 174.2 | 185 | 120 | 114 | 18 | 85 | 150 | 1 | 0 | 0 | 1 | 13 | 7 | 4 | 4.21 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 86 | 0 | 4 | 2 | 4.33 | .330 | 1.48 | 7.3 | 6.1 | 11.6 | 62.1 | 50 | 34 | 30 | 7 | 42 | 80 | 0 | 2 | 2 | 0 | 0 | 0 | 6 | 3.92 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 54 | 0 | 3 | 1 | 5.64 | .298 | 1.28 | 9.2 | 2.5 | 7.0 | 44.2 | 45 | 30 | 28 | 7 | 12 | 34 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.34 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 50 | 0 | 1 | 2 | 3.67 | .289 | 1.22 | 6.8 | 4.2 | 8.8 | 54.0 | 41 | 22 | 22 | 7 | 25 | 53 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 4.11 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 67 | 0 | 4 | 0 | 3.26 | .253 | 1.02 | 6.2 | 2.9 | 6.1 | 58.0 | 40 | 21 | 21 | 4 | 19 | 39 | 0 | 2 | 1 | 0 | 0 | 0 | 7 | 3.53 |
| SU | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 49 | 0 | 0 | 5 | 6.33 | .358 | 1.63 | 7.3 | 7.5 | 10.5 | 48.1 | 39 | 35 | 34 | 7 | 40 | 56 | 0 | 7 | 4 | 0 | 0 | 2 | 1 | 5.19 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 93 | 59 | 0 | 7 | 7 | 2.86 | .336 | 1.50 | 8.2 | 5.3 | 9.1 | 66.0 | 60 | 21 | 21 | 5 | 39 | 67 | 0 | 27 | 4 | 0 | 0 | 1 | 0 | 3.77 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 36 | 0 | 4 | 1 | 3.15 | .294 | 1.25 | 7.7 | 3.6 | 9.9 | 40.0 | 34 | 15 | 14 | 7 | 16 | 44 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.28 |