| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 32 | 32 | 9 | 12 | 4.55 | .322 | 1.41 | 9.9 | 2.8 | 4.8 | 170.0 | 187 | 89 | 86 | 21 | 53 | 90 | 0 | 0 | 0 | 0 | 14 | 2 | 3 | 4.52 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 32 | 32 | 7 | 18 | 4.41 | .322 | 1.40 | 9.9 | 2.8 | 4.0 | 222.2 | 243 | 119 | 109 | 16 | 68 | 98 | 6 | 0 | 0 | 0 | 14 | 6 | 6 | 4.05 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 32 | 32 | 9 | 12 | 5.19 | .330 | 1.43 | 10.4 | 2.6 | 4.0 | 218.1 | 251 | 130 | 126 | 28 | 62 | 96 | 1 | 0 | 0 | 0 | 13 | 10 | 1 | 4.78 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 29 | 29 | 12 | 10 | 3.85 | .307 | 1.30 | 8.2 | 3.5 | 6.0 | 210.1 | 192 | 96 | 90 | 14 | 82 | 140 | 6 | 0 | 0 | 2 | 16 | 6 | 4 | 3.79 |
| RP | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 86 | 0 | 9 | 4 | 2.40 | .271 | 1.10 | 6.4 | 3.5 | 9.1 | 116.1 | 83 | 32 | 31 | 7 | 45 | 117 | 0 | 7 | 6 | 0 | 0 | 2 | 2 | 2.98 |
| RP | Gallegos, G.Gallegos, Giovanny † >> | 27 | 2019 | R | 82 | 82 | 0 | 8 | 3 | 3.51 | .287 | 1.19 | 7.4 | 3.4 | 8.6 | 102.2 | 84 | 40 | 40 | 11 | 38 | 98 | 0 | 10 | 5 | 0 | 0 | 2 | 4 | 3.66 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 69 | 75 | 0 | 5 | 5 | 3.24 | .291 | 1.21 | 7.5 | 3.5 | 7.0 | 91.2 | 76 | 33 | 33 | 7 | 35 | 71 | 0 | 14 | 2 | 0 | 0 | 2 | 1 | 3.66 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 8 | 3 | 2 | 1 | 4.23 | .320 | 1.41 | 9.7 | 3.3 | 4.7 | 27.2 | 29 | 13 | 13 | 3 | 10 | 14 | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 4.52 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 28 | 0 | 4 | 4 | 3.72 | .331 | 1.47 | 7.3 | 5.9 | 6.1 | 58.0 | 47 | 26 | 24 | 6 | 38 | 39 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 5.02 |