| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 27 | 27 | 11 | 7 | 4.47 | .306 | 1.30 | 8.9 | 2.9 | 8.7 | 183.1 | 181 | 94 | 91 | 27 | 58 | 176 | 1 | 0 | 0 | 0 | 13 | 3 | 0 | 3.99 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 27 | 27 | 13 | 9 | 3.36 | .291 | 1.22 | 8.3 | 2.7 | 8.6 | 211.2 | 195 | 85 | 79 | 23 | 63 | 201 | 11 | 0 | 0 | 3 | 17 | 2 | 2 | 3.44 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 26 | 26 | 9 | 9 | 5.53 | .317 | 1.39 | 9.7 | 2.8 | 5.1 | 140.0 | 151 | 88 | 86 | 16 | 43 | 80 | 0 | 0 | 0 | 0 | 7 | 1 | 1 | 4.29 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 25 | 25 | 4 | 16 | 7.33 | .379 | 1.78 | 12.5 | 3.5 | 4.6 | 158.1 | 220 | 135 | 129 | 23 | 62 | 80 | 5 | 0 | 0 | 0 | 9 | 8 | 8 | 5.21 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 65 | 0 | 6 | 2 | 3.31 | .279 | 1.15 | 7.4 | 2.9 | 8.5 | 92.1 | 76 | 38 | 34 | 14 | 30 | 87 | 0 | 6 | 6 | 0 | 0 | 1 | 0 | 4.10 |
| RP | Eckersley, D.Eckersley, Dennis † >> | 36 | 1990 | R | 87 | 64 | 0 | 7 | 3 | 2.19 | .254 | 1.02 | 7.2 | 2.0 | 7.7 | 82.1 | 66 | 23 | 20 | 5 | 18 | 70 | 0 | 13 | 0 | 0 | 0 | 0 | 0 | 2.74 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 49 | 0 | 6 | 1 | 2.22 | .308 | 1.34 | 6.2 | 6.0 | 10.1 | 48.2 | 33 | 12 | 12 | 3 | 32 | 54 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.56 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 1 | 0 | 0 | 0 | 2.45 | .353 | 1.64 | 12.0 | 6.0 | 9.0 | 3.2 | 4 | 1 | 1 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 10 | 0 | 1 | 3 | 6.32 | .338 | 1.53 | 9.6 | 4.8 | 4.8 | 15.2 | 16 | 11 | 11 | 2 | 8 | 8 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 5.27 |