| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 29 | 29 | 13 | 9 | 3.74 | .264 | 1.06 | 7.8 | 1.8 | 8.2 | 204.2 | 176 | 85 | 85 | 20 | 40 | 186 | 6 | 0 | 0 | 2 | 18 | 4 | 5 | 3.10 |
| SP | Richard, J.Richard, J.R. † >> | 30 | 1980 | R | 90 | 28 | 28 | 14 | 10 | 3.12 | .297 | 1.25 | 7.0 | 4.3 | 8.3 | 190.2 | 147 | 67 | 66 | 9 | 91 | 175 | 1 | 0 | 0 | 0 | 22 | 4 | 3 | 3.27 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 28 | 28 | 8 | 6 | 3.38 | .281 | 1.16 | 8.0 | 2.5 | 5.3 | 154.2 | 137 | 61 | 58 | 10 | 43 | 91 | 0 | 0 | 0 | 0 | 8 | 1 | 2 | 3.52 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 26 | 23 | 9 | 8 | 3.32 | .293 | 1.22 | 7.0 | 4.0 | 7.5 | 170.2 | 133 | 71 | 63 | 18 | 75 | 142 | 0 | 0 | 0 | 0 | 17 | 4 | 3 | 4.10 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 22 | 22 | 12 | 4 | 2.94 | .289 | 1.22 | 6.4 | 4.6 | 7.9 | 144.0 | 102 | 53 | 47 | 8 | 74 | 127 | 0 | 0 | 0 | 0 | 16 | 0 | 10 | 3.50 |
| SU | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 42 | 0 | 1 | 1 | 3.66 | .278 | 1.14 | 5.9 | 4.5 | 8.2 | 46.2 | 30 | 20 | 19 | 4 | 23 | 42 | 0 | 3 | 5 | 0 | 0 | 1 | 1 | 3.87 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 70 | 0 | 4 | 1 | 2.92 | .269 | 1.08 | 7.0 | 2.7 | 5.0 | 77.0 | 60 | 27 | 25 | 5 | 23 | 43 | 0 | 2 | 3 | 0 | 0 | 2 | 1 | 3.70 |
| RP | Valverde, J.Valverde, Jose † >> | 24 | 2003 | R | 63 | 45 | 0 | 10 | 1 | 1.69 | .284 | 1.13 | 5.6 | 4.5 | 10.9 | 48.0 | 30 | 9 | 9 | 3 | 24 | 58 | 0 | 2 | 2 | 0 | 0 | 3 | 1 | 3.08 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 14 | 0 | 0 | 0 | 1.31 | .205 | 0.77 | 5.4 | 1.8 | 9.0 | 20.2 | 12 | 3 | 3 | 0 | 4 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.60 |
| RP | Wagner, B.Wagner, Billy # >> | 28 | 1999 | L | 95 | 32 | 0 | 1 | 4 | 5.40 | .305 | 1.26 | 7.2 | 4.1 | 8.5 | 35.0 | 28 | 21 | 21 | 6 | 16 | 33 | 0 | 6 | 3 | 0 | 0 | 2 | 0 | 4.89 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 8 | 0 | 3 | 0 | 2.16 | .259 | 0.99 | 6.5 | 2.5 | 9.0 | 33.1 | 24 | 8 | 8 | 2 | 9 | 33 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 2.79 |