| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 29 | 29 | 12 | 14 | 3.80 | .274 | 1.12 | 7.3 | 2.8 | 9.0 | 199.0 | 162 | 90 | 84 | 27 | 61 | 200 | 0 | 0 | 0 | 0 | 22 | 2 | 0 | 3.70 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 89 | 28 | 28 | 6 | 15 | 6.08 | .361 | 1.69 | 11.3 | 3.9 | 9.2 | 171.2 | 215 | 117 | 116 | 26 | 75 | 174 | 2 | 0 | 0 | 1 | 11 | 1 | 4 | 4.27 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 28 | 28 | 8 | 14 | 5.89 | .347 | 1.58 | 10.6 | 3.6 | 8.3 | 185.0 | 217 | 128 | 121 | 35 | 75 | 170 | 1 | 0 | 0 | 0 | 9 | 3 | 12 | 4.89 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 28 | 28 | 9 | 15 | 5.18 | .344 | 1.52 | 10.2 | 3.5 | 4.5 | 186.0 | 210 | 115 | 107 | 17 | 73 | 94 | 3 | 0 | 0 | 1 | 13 | 10 | 9 | 4.52 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 76 | 0 | 5 | 3 | 3.67 | .261 | 1.03 | 6.5 | 2.8 | 9.5 | 103.0 | 74 | 43 | 42 | 12 | 32 | 109 | 0 | 10 | 5 | 0 | 0 | 3 | 0 | 3.42 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 45 | 0 | 2 | 1 | 4.50 | .327 | 1.42 | 8.8 | 4.0 | 10.6 | 50.0 | 49 | 29 | 25 | 7 | 22 | 59 | 0 | 8 | 2 | 0 | 0 | 2 | 1 | 3.90 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 28 | 0 | 1 | 2 | 2.87 | .258 | 1.04 | 6.7 | 2.7 | 8.4 | 47.0 | 35 | 15 | 15 | 3 | 14 | 44 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 2.85 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 3 | 0 | 1 | 1 | 1.50 | .280 | 1.17 | 3.0 | 7.5 | 4.5 | 6.0 | 2 | 1 | 1 | 0 | 5 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.50 |