| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 93 | 29 | 29 | 9 | 11 | 3.94 | .290 | 1.20 | 7.7 | 3.1 | 7.1 | 178.1 | 153 | 83 | 78 | 17 | 61 | 140 | 0 | 0 | 0 | 0 | 18 | 5 | 5 | 3.78 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 28 | 28 | 11 | 8 | 3.86 | .282 | 1.16 | 7.2 | 3.3 | 5.1 | 174.2 | 140 | 79 | 75 | 9 | 63 | 99 | 2 | 0 | 0 | 2 | 17 | 3 | 3 | 3.67 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 28 | 28 | 14 | 7 | 2.67 | .255 | 1.01 | 7.3 | 1.8 | 5.3 | 199.0 | 162 | 66 | 59 | 14 | 39 | 118 | 4 | 0 | 0 | 1 | 23 | 3 | 2 | 3.36 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 81 | 0 | 5 | 5 | 2.57 | .287 | 1.19 | 5.6 | 5.2 | 9.1 | 101.2 | 63 | 31 | 29 | 7 | 58 | 102 | 0 | 9 | 6 | 0 | 0 | 2 | 2 | 3.66 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 50 | 0 | 4 | 7 | 4.38 | .330 | 1.46 | 7.3 | 5.9 | 8.8 | 49.1 | 40 | 24 | 24 | 10 | 32 | 48 | 0 | 9 | 2 | 0 | 0 | 1 | 1 | 5.71 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 30 | 0 | 1 | 1 | 2.45 | .236 | 0.93 | 6.5 | 2.0 | 6.0 | 36.2 | 26 | 10 | 10 | 1 | 8 | 24 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.69 |
| RP | Eichhorn, M.Eichhorn, Mark # >> | 26 | 1986 | R | 48 | 33 | 0 | 3 | 6 | 6.47 | .324 | 1.41 | 9.7 | 3.0 | 7.0 | 64.0 | 69 | 46 | 46 | 3 | 21 | 50 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 3.13 |