| SP | Skubal, T.Skubal, Tarik † $$ >> | 28 | 2025 | L | 100 | 30 | 30 | 13 | 5 | 2.82 | .248 | 0.99 | 6.9 | 2.0 | 9.8 | 211.0 | 161 | 68 | 66 | 19 | 47 | 230 | 3 | 0 | 0 | 1 | 19 | 1 | 4 | 2.67 |
| SP | Eovaldi, N.Eovaldi, Nathan $$ >> | 35 | 2025 | R | 98 | 30 | 30 | 12 | 7 | 3.19 | .297 | 1.24 | 8.5 | 2.7 | 8.0 | 191.2 | 180 | 69 | 68 | 12 | 58 | 170 | 1 | 0 | 0 | 1 | 21 | 5 | 10 | 3.03 |
| SP | Rogers, T.Rogers, Trevor $$ >> | 27 | 2025 | L | 97 | 28 | 28 | 17 | 8 | 3.40 | .279 | 1.14 | 7.2 | 3.1 | 8.4 | 174.2 | 139 | 70 | 66 | 22 | 60 | 162 | 1 | 0 | 0 | 1 | 19 | 4 | 0 | 3.89 |
| SP | Peralta, F.Peralta, Freddy $$ >> | 29 | 2025 | R | 89 | 29 | 29 | 13 | 7 | 3.67 | .314 | 1.35 | 7.7 | 4.5 | 9.4 | 154.1 | 132 | 64 | 63 | 19 | 77 | 161 | 0 | 0 | 0 | 0 | 8 | 3 | 5 | 4.07 |
| SP | Imanaga, S.Imanaga, Shota >> | 31 | 2025 | L | 83 | 29 | 27 | 16 | 7 | 3.30 | .283 | 1.18 | 8.3 | 2.3 | 7.6 | 166.1 | 154 | 68 | 61 | 11 | 42 | 141 | 0 | 1 | 0 | 0 | 16 | 1 | 3 | 2.94 |
| RP | Miller, M.Miller, Mason >> | 26 | 2025 | R | 98 | 87 | 0 | 3 | 0 | 2.93 | .290 | 1.16 | 5.6 | 4.9 | 12.0 | 89.0 | 55 | 29 | 29 | 8 | 48 | 119 | 0 | 2 | 2 | 0 | 0 | 6 | 4 | 3.31 |
| RP | Thielbar, C.Thielbar, Caleb >> | 38 | 2025 | L | 92 | 104 | 0 | 5 | 2 | 2.58 | .287 | 1.15 | 7.7 | 2.7 | 8.7 | 69.2 | 59 | 22 | 20 | 5 | 21 | 67 | 0 | 3 | 1 | 0 | 0 | 4 | 0 | 3.09 |
| RP | Hoffman, J.Hoffman, Jeff >> | 32 | 2025 | R | 60 | 44 | 0 | 3 | 2 | 4.23 | .306 | 1.28 | 8.4 | 3.3 | 11.0 | 44.2 | 41 | 21 | 21 | 7 | 16 | 54 | 0 | 4 | 2 | 0 | 0 | 2 | 1 | 3.84 |