| SP | Scherzer, M.Scherzer, Max † >> | 35 | 2019 | R | 94 | 36 | 36 | 14 | 8 | 3.89 | .276 | 1.11 | 7.7 | 2.4 | 11.7 | 224.1 | 191 | 103 | 97 | 29 | 59 | 290 | 1 | 0 | 0 | 1 | 23 | 6 | 0 | 2.96 |
| SP | Voth, A.Voth, Austin # >> | 27 | 2019 | R | 90 | 35 | 35 | 9 | 9 | 4.32 | .313 | 1.33 | 8.9 | 3.1 | 10.7 | 162.1 | 160 | 83 | 78 | 32 | 56 | 193 | 0 | 0 | 0 | 0 | 3 | 6 | 0 | 4.33 |
| SP | Samardzija, J.Samardzija, Jeff >> | 34 | 2019 | R | 80 | 34 | 34 | 11 | 11 | 4.57 | .308 | 1.31 | 8.6 | 3.2 | 7.1 | 181.0 | 173 | 93 | 92 | 31 | 65 | 142 | 0 | 0 | 0 | 0 | 16 | 4 | 4 | 4.80 |
| SP | Bassitt, C.Bassitt, Chris >> | 30 | 2019 | R | 75 | 33 | 33 | 10 | 7 | 5.44 | .345 | 1.56 | 9.5 | 4.5 | 8.4 | 149.0 | 158 | 98 | 90 | 38 | 74 | 139 | 0 | 0 | 0 | 0 | 7 | 3 | 3 | 6.00 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 29 | 2019 | R | 68 | 36 | 31 | 12 | 12 | 5.12 | .320 | 1.38 | 9.6 | 2.9 | 8.7 | 170.2 | 181 | 106 | 97 | 31 | 55 | 165 | 0 | 0 | 1 | 0 | 12 | 5 | 6 | 4.49 |
| CL | Rivero, F.Rivero, Felipe † >> | 27 | 2019 | L | 94 | 75 | 0 | 6 | 3 | 3.40 | .298 | 1.25 | 8.5 | 2.7 | 12.8 | 79.1 | 75 | 34 | 30 | 11 | 24 | 112 | 0 | 29 | 4 | 0 | 0 | 2 | 2 | 2.96 |
| SU | Bummer, A.Bummer, Aaron >> | 25 | 2019 | L | 87 | 85 | 0 | 7 | 1 | 3.40 | .285 | 1.17 | 6.8 | 3.7 | 9.0 | 92.2 | 70 | 39 | 35 | 15 | 38 | 92 | 0 | 6 | 8 | 0 | 0 | 3 | 1 | 4.46 |
| RP | Kahnle, T.Kahnle, Tommy >> | 29 | 2019 | R | 82 | 102 | 0 | 9 | 4 | 4.78 | .323 | 1.40 | 8.0 | 4.5 | 11.4 | 111.0 | 99 | 62 | 59 | 16 | 56 | 141 | 0 | 2 | 6 | 0 | 0 | 4 | 15 | 3.95 |
| RP | Wingenter, T.Wingenter, Trey >> | 25 | 2019 | R | 78 | 92 | 0 | 8 | 3 | 2.60 | .292 | 1.23 | 6.1 | 5.0 | 10.7 | 103.2 | 70 | 36 | 30 | 11 | 57 | 123 | 0 | 2 | 2 | 0 | 0 | 1 | 5 | 3.69 |
| RP | Robles, H.Robles, Hansel >> | 28 | 2019 | R | 77 | 75 | 0 | 8 | 5 | 3.27 | .305 | 1.27 | 8.5 | 3.0 | 10.8 | 88.0 | 83 | 34 | 32 | 11 | 29 | 106 | 0 | 4 | 2 | 0 | 0 | 4 | 6 | 3.34 |
| RP | Givens, M.Givens, Mychal >> | 29 | 2019 | R | 74 | 67 | 0 | 3 | 1 | 4.78 | .322 | 1.42 | 8.6 | 4.2 | 13.8 | 64.0 | 61 | 37 | 34 | 14 | 30 | 98 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 4.19 |
| RP | Taylor, J.Taylor, Josh >> | 26 | 2019 | L | 69 | 102 | 0 | 5 | 3 | 4.41 | .310 | 1.30 | 8.5 | 3.1 | 9.6 | 98.0 | 93 | 51 | 48 | 16 | 34 | 105 | 0 | 1 | 2 | 0 | 0 | 5 | 5 | 4.17 |