| SP | Garcia, F.Garcia, Freddy >> | 26 | 2001 | R | 61 | 10 | 10 | 5 | 3 | 4.43 | .315 | 1.35 | 9.0 | 3.1 | 5.1 | 69.0 | 69 | 36 | 34 | 8 | 24 | 39 | 3 | 0 | 0 | 0 | 6 | 2 | 1 | 4.51 |
| SP | Clement, M.Clement, Matt >> | 28 | 2002 | R | 54 | 11 | 11 | 2 | 5 | 5.72 | .352 | 1.63 | 9.3 | 5.5 | 9.0 | 61.1 | 63 | 39 | 39 | 11 | 37 | 61 | 0 | 0 | 0 | 0 | 5 | 0 | 4 | 5.16 |
| SP | Harang, A.Harang, Aaron >> | 29 | 2007 | R | 51 | 10 | 10 | 1 | 8 | 7.82 | .378 | 1.78 | 12.8 | 3.4 | 6.9 | 48.1 | 68 | 45 | 42 | 11 | 18 | 37 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 5.69 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 27 | 0 | 1 | 0 | 2.55 | .244 | 0.94 | 6.2 | 2.4 | 8.6 | 42.1 | 29 | 12 | 12 | 3 | 11 | 40 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 2.88 |
| RP | Takatsu, S.Takatsu, Shingo >> | 36 | 2004 | R | 57 | 26 | 0 | 1 | 3 | 5.46 | .352 | 1.60 | 7.8 | 6.7 | 7.3 | 31.1 | 27 | 19 | 19 | 6 | 23 | 25 | 0 | 1 | 3 | 0 | 0 | 1 | 1 | 6.23 |
| RP | Hawkins, L.Hawkins, LaTroy >> | 30 | 2002 | R | 40 | 21 | 0 | 1 | 1 | 4.25 | .310 | 1.35 | 9.9 | 2.5 | 7.4 | 29.2 | 32 | 14 | 14 | 4 | 8 | 24 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.97 |
| RP | Cordero, F.Cordero, Francisco >> | 32 | 2007 | R | 27 | 21 | 0 | 0 | 3 | 3.65 | .308 | 1.30 | 9.8 | 2.3 | 10.9 | 24.2 | 26 | 10 | 10 | 3 | 6 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.08 |
| RP | Ziegler, B.Ziegler, Brad >> | 29 | 2008 | R | 15 | 16 | 0 | 1 | 0 | 5.24 | .295 | 1.16 | 8.6 | 2.0 | 4.9 | 22.1 | 21 | 13 | 13 | 3 | 5 | 12 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.64 |
| SP | Kazmir, S.Kazmir, Scott >> | 24 | 2008 | L | 40 | 10 | 1 | 1 | 0 | 6.61 | .364 | 1.65 | 10.7 | 4.5 | 8.4 | 16.1 | 19 | 12 | 12 | 4 | 8 | 15 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 6.06 |