| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 11 | 11 | 5 | 2 | 3.66 | .284 | 1.16 | 5.6 | 4.9 | 10.1 | 66.1 | 41 | 29 | 27 | 10 | 36 | 74 | 0 | 0 | 0 | 0 | 6 | 2 | 0 | 4.45 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 84 | 11 | 11 | 6 | 2 | 3.70 | .292 | 1.22 | 8.4 | 2.6 | 6.5 | 75.1 | 70 | 31 | 31 | 13 | 22 | 54 | 1 | 0 | 0 | 1 | 7 | 1 | 0 | 4.73 |
| SP | Perez, O.Perez, Oliver >> | 23 | 2004 | L | 76 | 10 | 10 | 0 | 7 | 7.21 | .376 | 1.75 | 10.5 | 5.4 | 10.3 | 48.2 | 56 | 46 | 39 | 11 | 29 | 55 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 5.69 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 10 | 10 | 3 | 4 | 4.11 | .289 | 1.16 | 8.4 | 2.1 | 8.2 | 65.2 | 61 | 30 | 30 | 13 | 15 | 59 | 1 | 0 | 0 | 1 | 6 | 4 | 0 | 4.66 |
| CL | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 91 | 21 | 0 | 1 | 3 | 5.06 | .360 | 1.56 | 10.1 | 3.9 | 7.3 | 16.0 | 18 | 9 | 9 | 2 | 7 | 13 | 0 | 9 | 2 | 0 | 0 | 2 | 0 | 4.69 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 87 | 24 | 0 | 3 | 1 | 1.93 | .253 | 1.02 | 8.0 | 1.5 | 8.5 | 18.2 | 16 | 4 | 4 | 3 | 3 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.78 |
| RP | Wagner, B.Wagner, Billy >> | 32 | 2003 | L | 90 | 28 | 0 | 2 | 0 | 4.30 | .290 | 1.23 | 7.1 | 4.5 | 6.4 | 14.2 | 11 | 7 | 7 | 1 | 7 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.00 |
| RP | Linebrink, S.Linebrink, Scott >> | 28 | 2004 | R | 45 | 10 | 0 | 0 | 1 | 13.50 | .500 | 3.00 | 25.2 | 3.6 | 7.2 | 5.1 | 14 | 8 | 8 | 1 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.20 |
| SP | Verlander, J.Verlander, Justin >> | 26 | 2009 | R | 42 | 8 | 0 | 0 | 0 | 4.50 | .364 | 1.66 | 10.7 | 4.2 | 8.4 | 32.0 | 38 | 21 | 16 | 3 | 15 | 30 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 3.94 |