| SP | Schmidt, J.Schmidt, Jason † # >> | 30 | 2003 | R | 99 | 26 | 26 | 15 | 8 | 3.41 | .264 | 1.06 | 7.2 | 2.4 | 9.0 | 197.2 | 158 | 83 | 75 | 21 | 52 | 197 | 9 | 0 | 0 | 1 | 15 | 3 | 3 | 3.22 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 84 | 25 | 25 | 12 | 9 | 4.44 | .315 | 1.36 | 9.2 | 3.0 | 6.2 | 162.0 | 166 | 80 | 80 | 17 | 54 | 112 | 1 | 0 | 0 | 1 | 15 | 4 | 4 | 4.06 |
| SP | Williams, W.Williams, Woody # >> | 36 | 2002 | R | 79 | 25 | 25 | 9 | 9 | 5.30 | .354 | 1.62 | 10.8 | 3.7 | 6.2 | 146.0 | 176 | 98 | 86 | 27 | 60 | 101 | 0 | 0 | 0 | 0 | 14 | 4 | 4 | 5.34 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 67 | 25 | 25 | 10 | 8 | 6.16 | .365 | 1.69 | 11.5 | 3.7 | 5.3 | 149.0 | 191 | 104 | 102 | 28 | 61 | 87 | 0 | 0 | 0 | 0 | 8 | 5 | 1 | 5.60 |
| SP | Millwood, K.Millwood, Kevin >> | 28 | 2002 | R | 52 | 24 | 24 | 9 | 9 | 6.14 | .353 | 1.59 | 11.6 | 2.8 | 6.2 | 143.2 | 184 | 101 | 98 | 25 | 45 | 98 | 0 | 0 | 0 | 0 | 8 | 6 | 3 | 4.97 |
| RP | Percival, T.Percival, Troy >> | 38 | 2007 | R | 84 | 56 | 0 | 7 | 2 | 3.32 | .272 | 1.11 | 6.8 | 3.2 | 6.0 | 76.0 | 57 | 28 | 28 | 8 | 27 | 51 | 0 | 5 | 3 | 0 | 0 | 1 | 2 | 4.13 |
| RP | Wheeler, D.Wheeler, Dan >> | 32 | 2009 | R | 67 | 47 | 0 | 6 | 2 | 5.86 | .305 | 1.30 | 9.5 | 2.3 | 6.4 | 55.1 | 58 | 36 | 36 | 14 | 14 | 39 | 0 | 5 | 3 | 0 | 0 | 1 | 3 | 5.71 |
| RP | Williamson, S.Williamson, Scott >> | 26 | 2002 | R | 52 | 31 | 0 | 2 | 0 | 5.94 | .363 | 1.62 | 8.5 | 6.3 | 10.6 | 33.1 | 31 | 22 | 22 | 7 | 23 | 39 | 0 | 2 | 1 | 0 | 0 | 3 | 2 | 5.76 |
| RP | Guerrier, M.Guerrier, Matt >> | 31 | 2009 | R | 42 | 35 | 0 | 0 | 0 | 4.72 | .319 | 1.32 | 9.2 | 2.9 | 5.9 | 47.2 | 48 | 25 | 25 | 7 | 15 | 31 | 0 | 0 | 0 | 0 | 0 | 4 | 6 | 4.83 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 48 | 13 | 0 | 3 | 0 | 4.26 | .337 | 1.53 | 10.4 | 3.3 | 8.1 | 19.0 | 22 | 9 | 9 | 5 | 7 | 17 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.74 |