| SP | Lincecum, T.Lincecum, Tim # >> | 25 | 2009 | R | 92 | 26 | 26 | 7 | 13 | 4.88 | .310 | 1.30 | 8.8 | 2.9 | 8.9 | 169.2 | 166 | 92 | 92 | 20 | 55 | 167 | 1 | 0 | 0 | 0 | 13 | 8 | 6 | 3.68 |
| SP | Bedard, E.Bedard, Erik # >> | 28 | 2007 | L | 80 | 25 | 25 | 8 | 8 | 5.29 | .338 | 1.52 | 9.3 | 4.3 | 8.7 | 143.0 | 148 | 84 | 84 | 21 | 69 | 139 | 1 | 0 | 0 | 0 | 11 | 2 | 4 | 4.45 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 25 | 25 | 7 | 10 | 5.27 | .330 | 1.44 | 10.3 | 2.6 | 5.8 | 147.0 | 169 | 88 | 86 | 23 | 42 | 95 | 0 | 0 | 0 | 0 | 11 | 6 | 1 | 4.72 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 68 | 25 | 25 | 8 | 6 | 5.43 | .344 | 1.54 | 10.8 | 3.1 | 7.1 | 131.0 | 157 | 79 | 79 | 23 | 45 | 103 | 0 | 0 | 0 | 0 | 11 | 4 | 3 | 4.83 |
| SP | Maddux, G.Maddux, Greg >> | 34 | 2000 | R | 58 | 23 | 23 | 9 | 7 | 5.26 | .324 | 1.39 | 9.3 | 3.2 | 6.8 | 142.0 | 146 | 83 | 83 | 21 | 51 | 107 | 3 | 0 | 0 | 0 | 10 | 7 | 1 | 4.64 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 89 | 59 | 0 | 5 | 3 | 2.80 | .295 | 1.22 | 8.2 | 2.8 | 9.0 | 80.1 | 73 | 27 | 25 | 12 | 25 | 80 | 0 | 8 | 4 | 0 | 0 | 3 | 0 | 4.00 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 87 | 48 | 0 | 5 | 3 | 1.98 | .245 | 0.93 | 6.4 | 2.0 | 8.7 | 63.2 | 45 | 14 | 14 | 7 | 14 | 61 | 0 | 4 | 1 | 0 | 0 | 3 | 0 | 3.32 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 39 | 0 | 3 | 3 | 4.44 | .289 | 1.14 | 8.8 | 1.6 | 10.4 | 46.2 | 45 | 23 | 23 | 8 | 8 | 53 | 0 | 4 | 1 | 0 | 0 | 4 | 2 | 3.74 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 64 | 28 | 0 | 3 | 2 | 4.70 | .343 | 1.53 | 11.1 | 3.0 | 6.0 | 30.2 | 37 | 16 | 16 | 4 | 10 | 20 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.50 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 59 | 28 | 0 | 1 | 0 | 4.02 | .304 | 1.31 | 9.0 | 2.9 | 10.5 | 31.1 | 31 | 14 | 14 | 2 | 10 | 36 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 2.48 |