| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 31 | 31 | 10 | 11 | 4.75 | .314 | 1.34 | 8.4 | 3.6 | 8.1 | 195.1 | 183 | 111 | 103 | 27 | 78 | 176 | 2 | 0 | 0 | 1 | 14 | 7 | 1 | 4.30 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 30 | 30 | 7 | 19 | 5.98 | .338 | 1.51 | 10.0 | 3.6 | 4.3 | 191.0 | 212 | 130 | 127 | 30 | 77 | 92 | 3 | 0 | 0 | 0 | 11 | 3 | 0 | 5.34 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 71 | 29 | 29 | 8 | 16 | 4.70 | .315 | 1.37 | 9.9 | 2.4 | 4.4 | 214.1 | 235 | 114 | 112 | 22 | 58 | 104 | 9 | 0 | 0 | 1 | 11 | 3 | 6 | 4.22 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 78 | 0 | 5 | 2 | 3.02 | .295 | 1.25 | 7.2 | 4.1 | 7.4 | 101.1 | 81 | 35 | 34 | 7 | 46 | 83 | 0 | 7 | 2 | 0 | 0 | 0 | 2 | 3.62 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 67 | 0 | 5 | 2 | 2.46 | .275 | 1.13 | 6.8 | 3.4 | 8.0 | 87.2 | 66 | 29 | 24 | 10 | 33 | 77 | 0 | 8 | 3 | 0 | 0 | 1 | 1 | 3.90 |
| RP | Rincon, J.Rincon, Juan # >> | 25 | 2004 | R | 43 | 40 | 0 | 1 | 4 | 6.75 | .340 | 1.54 | 9.2 | 4.9 | 8.0 | 46.2 | 47 | 36 | 35 | 3 | 25 | 41 | 0 | 1 | 3 | 0 | 0 | 0 | 1 | 3.70 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 2 | 0 | 0 | 0 | 0.00 | .125 | 0.43 | 0.0 | 4.5 | 4.5 | 2.1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.50 |
| SP | Cuellar, M.Cuellar, Mike >> | 32 | 1969 | L | 43 | 19 | 0 | 2 | 1 | 7.02 | .379 | 1.80 | 11.2 | 5.2 | 4.9 | 33.1 | 41 | 27 | 26 | 4 | 19 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.30 |