| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 30 | 30 | 11 | 14 | 3.81 | .289 | 1.22 | 8.9 | 2.0 | 5.7 | 212.1 | 210 | 91 | 90 | 9 | 48 | 135 | 5 | 0 | 0 | 0 | 18 | 1 | 3 | 2.97 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 30 | 30 | 9 | 11 | 5.65 | .352 | 1.61 | 11.3 | 3.3 | 7.9 | 184.2 | 230 | 123 | 116 | 26 | 67 | 162 | 2 | 0 | 0 | 1 | 11 | 4 | 10 | 4.23 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 29 | 29 | 7 | 13 | 4.86 | .319 | 1.38 | 9.3 | 3.2 | 4.7 | 185.1 | 191 | 107 | 100 | 20 | 65 | 97 | 1 | 0 | 0 | 0 | 12 | 4 | 1 | 4.48 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 81 | 49 | 0 | 7 | 4 | 4.36 | .290 | 1.22 | 9.2 | 1.9 | 8.6 | 43.1 | 44 | 22 | 21 | 7 | 9 | 41 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 3.84 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 22 | 0 | 1 | 0 | 1.69 | .264 | 1.03 | 6.4 | 3.0 | 4.3 | 21.1 | 15 | 6 | 4 | 2 | 7 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.43 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 12 | 0 | 1 | 2 | 6.52 | .370 | 1.66 | 9.0 | 7.0 | 7.0 | 9.2 | 9 | 7 | 7 | 2 | 7 | 7 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 7.00 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 11 | 0 | 0 | 1 | 4.76 | .333 | 1.41 | 8.2 | 4.9 | 9.8 | 11.1 | 10 | 6 | 6 | 0 | 6 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.73 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 24 | 0 | 0 | 1 | 4.10 | .295 | 1.25 | 7.3 | 4.2 | 11.1 | 26.1 | 21 | 14 | 12 | 4 | 12 | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.92 |
| CL | Benoit, J.Benoit, Joaquin $ >> | 33 | 2010 | R | 95 | 52 | 0 | 1 | 10 | 4.88 | .332 | 1.49 | 9.2 | 4.4 | 8.1 | 51.2 | 52 | 30 | 28 | 7 | 25 | 46 | 0 | 26 | 7 | 0 | 0 | 0 | 1 | 4.45 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 17 | 0 | 0 | 1 | 6.44 | .367 | 1.70 | 11.9 | 3.6 | 5.1 | 58.2 | 77 | 45 | 42 | 14 | 23 | 33 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 6.29 |