| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 31 | 31 | 11 | 12 | 3.59 | .284 | 1.17 | 7.9 | 2.6 | 7.8 | 233.1 | 204 | 99 | 93 | 20 | 68 | 203 | 6 | 0 | 0 | 1 | 19 | 5 | 13 | 3.31 |
| SP | Nelson, R.Nelson, Roger # >> | 28 | 1972 | R | 84 | 31 | 31 | 9 | 7 | 3.55 | .308 | 1.33 | 9.2 | 2.8 | 5.5 | 169.2 | 173 | 69 | 67 | 13 | 53 | 103 | 0 | 0 | 0 | 0 | 8 | 1 | 4 | 3.74 |
| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 73 | 30 | 30 | 15 | 11 | 5.20 | .321 | 1.41 | 9.3 | 3.5 | 4.7 | 226.2 | 233 | 133 | 131 | 24 | 87 | 119 | 11 | 0 | 0 | 2 | 9 | 2 | 8 | 4.51 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 30 | 30 | 7 | 17 | 4.58 | .320 | 1.38 | 8.7 | 3.8 | 7.2 | 218.1 | 211 | 116 | 111 | 31 | 91 | 174 | 4 | 0 | 0 | 0 | 15 | 6 | 0 | 4.59 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 69 | 0 | 5 | 4 | 3.39 | .302 | 1.27 | 8.7 | 2.8 | 9.2 | 87.2 | 84 | 38 | 33 | 7 | 27 | 89 | 0 | 5 | 5 | 0 | 0 | 3 | 5 | 3.03 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 54 | 0 | 6 | 5 | 2.92 | .284 | 1.19 | 5.2 | 5.6 | 9.3 | 64.2 | 37 | 25 | 21 | 7 | 40 | 66 | 0 | 7 | 3 | 0 | 0 | 0 | 1 | 4.23 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 37 | 0 | 1 | 2 | 3.86 | .353 | 1.61 | 8.3 | 6.3 | 11.7 | 37.1 | 34 | 17 | 16 | 4 | 26 | 48 | 0 | 5 | 2 | 0 | 0 | 1 | 0 | 4.00 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 54 | 32 | 0 | 3 | 1 | 5.20 | .335 | 1.51 | 7.3 | 6.5 | 9.5 | 36.1 | 29 | 23 | 21 | 6 | 26 | 38 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.22 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 12 | 0 | 2 | 2 | 4.50 | .386 | 1.89 | 11.5 | 5.5 | 5.5 | 18.0 | 23 | 11 | 9 | 3 | 11 | 11 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 5.78 |