| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 31 | 31 | 9 | 11 | 3.95 | .295 | 1.23 | 8.0 | 3.1 | 9.7 | 212.0 | 189 | 101 | 93 | 21 | 72 | 228 | 4 | 0 | 0 | 2 | 18 | 5 | 8 | 3.23 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 11 | 1 | 1 | 2 | 4.89 | .347 | 1.58 | 10.7 | 3.6 | 6.8 | 53.1 | 63 | 35 | 29 | 6 | 21 | 40 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 4.21 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 29 | 29 | 9 | 14 | 5.13 | .337 | 1.51 | 10.4 | 3.2 | 7.9 | 187.2 | 216 | 118 | 107 | 32 | 67 | 165 | 0 | 0 | 0 | 0 | 14 | 3 | 2 | 4.58 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 30 | 30 | 11 | 12 | 5.67 | .348 | 1.59 | 9.8 | 4.5 | 5.4 | 182.2 | 198 | 129 | 115 | 15 | 92 | 110 | 5 | 0 | 0 | 0 | 11 | 2 | 9 | 4.41 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 65 | 0 | 2 | 4 | 4.35 | .341 | 1.52 | 8.6 | 5.2 | 8.1 | 68.1 | 65 | 34 | 33 | 8 | 39 | 61 | 0 | 0 | 2 | 0 | 0 | 2 | 1 | 4.54 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 67 | 0 | 5 | 5 | 5.00 | .329 | 1.46 | 9.4 | 3.8 | 8.0 | 72.0 | 75 | 44 | 40 | 10 | 30 | 64 | 0 | 0 | 3 | 0 | 0 | 1 | 2 | 4.32 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 40 | 0 | 2 | 2 | 5.44 | .325 | 1.42 | 8.2 | 4.6 | 5.9 | 43.0 | 39 | 29 | 26 | 6 | 22 | 28 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.12 |
| SU | Bailey, A.Bailey, Andrew $$ >> | 25 | 2009 | R | 66 | 53 | 0 | 2 | 3 | 3.52 | .306 | 1.27 | 7.5 | 4.1 | 9.2 | 53.2 | 44 | 21 | 21 | 8 | 24 | 54 | 0 | 2 | 5 | 0 | 0 | 3 | 1 | 4.45 |
| CL | Doolittle, S.Doolittle, Sean † $ >> | 31 | 2018 | L | 99 | 59 | 0 | 4 | 5 | 3.67 | .300 | 1.29 | 9.1 | 2.5 | 10.3 | 61.1 | 62 | 27 | 25 | 10 | 17 | 70 | 0 | 31 | 8 | 0 | 0 | 0 | 1 | 3.67 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 82 | 29 | 29 | 10 | 9 | 4.78 | .314 | 1.37 | 10.3 | 2.1 | 5.0 | 188.1 | 215 | 107 | 100 | 28 | 43 | 104 | 0 | 0 | 0 | 0 | 14 | 1 | 1 | 4.53 |