| SP | Koufax, S.Koufax, Sandy $$ >> | 30 | 1965 | L | 97 | 16 | 16 | 3 | 9 | 4.76 | .318 | 1.36 | 9.4 | 2.8 | 8.9 | 102.0 | 107 | 57 | 54 | 14 | 32 | 101 | 2 | 0 | 0 | 1 | 8 | 4 | 2 | 3.86 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 16 | 16 | 9 | 6 | 3.14 | .283 | 1.15 | 8.5 | 1.9 | 5.4 | 114.2 | 108 | 44 | 40 | 7 | 24 | 69 | 2 | 0 | 0 | 0 | 9 | 4 | 3 | 3.32 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 15 | 15 | 6 | 3 | 3.87 | .298 | 1.26 | 7.8 | 3.6 | 5.3 | 109.1 | 94 | 47 | 47 | 11 | 44 | 64 | 4 | 0 | 0 | 0 | 10 | 1 | 1 | 4.38 |
| SP | Coombs, J.Coombs, Jack >> | 28 | 1910 | R | 45 | 12 | 10 | 4 | 6 | 5.64 | .339 | 1.52 | 9.3 | 4.4 | 5.1 | 67.0 | 69 | 43 | 42 | 8 | 33 | 38 | 1 | 0 | 0 | 0 | 4 | 1 | 0 | 4.94 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 35 | 0 | 2 | 4 | 5.81 | .342 | 1.52 | 11.1 | 2.8 | 9.7 | 26.1 | 32 | 17 | 17 | 5 | 8 | 28 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.38 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 29 | 0 | 2 | 1 | 5.32 | .347 | 1.50 | 10.2 | 3.3 | 6.5 | 22.0 | 25 | 14 | 13 | 4 | 8 | 16 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.27 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 17 | 0 | 0 | 0 | 4.60 | .338 | 1.47 | 9.0 | 4.8 | 7.2 | 15.2 | 15 | 8 | 8 | 3 | 8 | 12 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 5.80 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 10 | 0 | 0 | 1 | 7.27 | .409 | 2.08 | 12.4 | 7.9 | 12.4 | 8.2 | 11 | 7 | 7 | 3 | 7 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.75 |
| RP | Bailey, A.Bailey, Andrew $ >> | 25 | 2009 | R | 67 | 14 | 0 | 0 | 1 | 8.10 | .474 | 2.60 | 13.5 | 9.9 | 8.1 | 10.0 | 15 | 9 | 9 | 1 | 11 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.10 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 23 | 0 | 1 | 1 | 1.13 | .258 | 0.96 | 4.9 | 3.8 | 7.9 | 24.0 | 13 | 4 | 3 | 1 | 10 | 21 | 0 | 21 | 2 | 0 | 0 | 2 | 0 | 3.29 |
| SP | Harden, R.Harden, Rich # >> | 27 | 2008 | R | 61 | 12 | 5 | 3 | 3 | 5.05 | .335 | 1.46 | 8.7 | 4.4 | 8.2 | 57.0 | 55 | 33 | 32 | 10 | 28 | 52 | 0 | 0 | 0 | 0 | 1 | 3 | 1 | 5.09 |