| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 39 | 39 | 24 | 7 | 3.38 | .274 | 1.10 | 7.2 | 2.7 | 8.4 | 279.2 | 224 | 113 | 105 | 27 | 85 | 260 | 6 | 0 | 0 | 0 | 30 | 8 | 11 | 3.39 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 99 | 39 | 39 | 13 | 5 | 3.70 | .284 | 1.16 | 7.5 | 3.0 | 8.0 | 192.1 | 160 | 82 | 79 | 18 | 63 | 171 | 0 | 0 | 0 | 0 | 6 | 6 | 9 | 3.52 |
| SP | Milton, E.Milton, Eric >> | 28 | 2003 | L | 89 | 37 | 37 | 18 | 8 | 3.95 | .306 | 1.29 | 9.5 | 2.1 | 4.3 | 230.1 | 244 | 106 | 101 | 23 | 53 | 111 | 1 | 0 | 0 | 0 | 23 | 7 | 0 | 4.12 |
| CL | Nathan, J.Nathan, Joe † >> | 32 | 2006 | R | 100 | 78 | 0 | 12 | 6 | 1.55 | .199 | 0.71 | 4.8 | 1.7 | 9.8 | 87.1 | 46 | 15 | 15 | 4 | 16 | 95 | 0 | 48 | 2 | 0 | 0 | 3 | 3 | 2.07 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 96 | 91 | 0 | 12 | 2 | 4.06 | .324 | 1.43 | 8.1 | 4.8 | 10.0 | 106.1 | 95 | 49 | 48 | 10 | 57 | 118 | 0 | 3 | 3 | 0 | 0 | 1 | 4 | 3.64 |
| RP | Mijares, J.Mijares, Jose >> | 24 | 2008 | L | 95 | 82 | 0 | 8 | 1 | 3.58 | .260 | 1.02 | 7.8 | 1.4 | 6.0 | 100.2 | 87 | 41 | 40 | 13 | 16 | 67 | 0 | 1 | 6 | 0 | 0 | 3 | 10 | 3.92 |
| RP | Reyes, D.Reyes, Dennys >> | 29 | 2006 | L | 94 | 59 | 0 | 5 | 3 | 4.92 | .338 | 1.47 | 9.0 | 4.2 | 6.2 | 64.0 | 64 | 36 | 35 | 5 | 30 | 44 | 0 | 2 | 2 | 0 | 0 | 4 | 9 | 4.23 |
| RP | Fuentes, B.Fuentes, Brian >> | 35 | 2010 | L | 93 | 36 | 0 | 3 | 2 | 3.63 | .350 | 1.62 | 9.5 | 5.3 | 7.9 | 34.2 | 36 | 14 | 14 | 3 | 20 | 30 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 4.15 |
| RP | Guardado, E.Guardado, Eddie >> | 31 | 2001 | L | 92 | 24 | 0 | 1 | 2 | 7.20 | .439 | 2.25 | 14.4 | 5.9 | 10.8 | 20.0 | 32 | 17 | 16 | 2 | 13 | 24 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.15 |
| RP | Hawkins, L.Hawkins, LaTroy >> | 30 | 2002 | R | 88 | 32 | 0 | 0 | 0 | 3.55 | .283 | 1.13 | 8.8 | 1.4 | 5.9 | 38.0 | 37 | 16 | 15 | 5 | 6 | 25 | 0 | 2 | 0 | 0 | 0 | 2 | 2 | 4.03 |