| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 20 | 20 | 10 | 7 | 3.77 | .301 | 1.28 | 9.4 | 2.1 | 5.1 | 143.1 | 150 | 67 | 60 | 10 | 33 | 81 | 4 | 0 | 0 | 0 | 12 | 2 | 4 | 3.51 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 19 | 19 | 8 | 9 | 4.59 | .326 | 1.43 | 9.1 | 3.8 | 8.5 | 113.2 | 114 | 60 | 58 | 15 | 48 | 107 | 1 | 0 | 0 | 0 | 7 | 3 | 2 | 4.19 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 19 | 19 | 6 | 6 | 6.01 | .344 | 1.53 | 9.8 | 4.1 | 8.4 | 100.1 | 109 | 72 | 67 | 24 | 45 | 93 | 0 | 0 | 0 | 0 | 9 | 4 | 5 | 5.73 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 18 | 18 | 5 | 8 | 5.12 | .320 | 1.39 | 10.3 | 2.2 | 6.4 | 116.0 | 133 | 75 | 66 | 14 | 28 | 83 | 3 | 0 | 0 | 1 | 7 | 3 | 3 | 3.94 |
| CL | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 39 | 0 | 3 | 2 | 4.85 | .301 | 1.29 | 7.3 | 4.5 | 7.3 | 42.2 | 34 | 23 | 23 | 3 | 21 | 34 | 0 | 14 | 3 | 0 | 0 | 0 | 4 | 3.81 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 55 | 0 | 1 | 0 | 3.75 | .276 | 1.13 | 6.4 | 3.8 | 6.8 | 48.0 | 34 | 20 | 20 | 1 | 20 | 36 | 0 | 0 | 0 | 0 | 0 | 1 | 7 | 3.08 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 13 | 0 | 1 | 1 | 1.32 | .305 | 1.32 | 7.6 | 4.8 | 10.4 | 13.2 | 11 | 2 | 2 | 1 | 7 | 15 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.31 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 56 | 0 | 1 | 1 | 3.56 | .342 | 1.56 | 8.1 | 6.0 | 10.5 | 48.0 | 43 | 24 | 19 | 7 | 32 | 56 | 0 | 2 | 0 | 0 | 0 | 0 | 5 | 4.56 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 31 | 0 | 3 | 2 | 5.08 | .366 | 1.69 | 11.9 | 3.5 | 7.1 | 28.1 | 37 | 20 | 16 | 1 | 11 | 22 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.18 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 42 | 9 | 0 | 0 | 1 | 6.10 | .354 | 1.65 | 11.7 | 3.6 | 9.0 | 10.1 | 13 | 8 | 7 | 0 | 4 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.20 |