| SP | Greinke, Z.Greinke, Zack # >> | 32 | 2015 | R | 94 | 23 | 23 | 9 | 10 | 5.28 | .338 | 1.52 | 9.4 | 4.3 | 6.0 | 145.0 | 151 | 90 | 85 | 22 | 70 | 97 | 0 | 0 | 0 | 0 | 12 | 1 | 5 | 5.10 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 22 | 22 | 11 | 9 | 4.76 | .314 | 1.36 | 9.4 | 3.0 | 8.6 | 143.2 | 149 | 78 | 76 | 21 | 47 | 136 | 0 | 0 | 0 | 0 | 10 | 1 | 2 | 4.01 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 22 | 22 | 7 | 6 | 3.53 | .305 | 1.30 | 8.1 | 3.6 | 8.6 | 135.0 | 122 | 67 | 53 | 16 | 54 | 129 | 0 | 0 | 0 | 0 | 13 | 2 | 2 | 3.87 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 22 | 22 | 11 | 7 | 4.71 | .284 | 1.13 | 8.8 | 1.4 | 5.8 | 154.2 | 150 | 88 | 81 | 22 | 24 | 100 | 8 | 0 | 0 | 1 | 9 | 10 | 4 | 4.22 |
| CL | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 34 | 0 | 3 | 1 | 4.37 | .318 | 1.40 | 8.5 | 4.1 | 8.0 | 35.0 | 33 | 18 | 17 | 4 | 16 | 31 | 0 | 12 | 3 | 0 | 0 | 0 | 0 | 4.09 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 50 | 52 | 0 | 1 | 1 | 3.35 | .319 | 1.38 | 9.5 | 3.2 | 7.8 | 37.2 | 39 | 17 | 14 | 2 | 13 | 32 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 3.11 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 45 | 0 | 3 | 1 | 3.19 | .310 | 1.32 | 8.8 | 3.2 | 6.4 | 42.1 | 41 | 18 | 15 | 3 | 15 | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.64 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 25 | 0 | 0 | 0 | 2.89 | .333 | 1.50 | 8.5 | 5.5 | 9.5 | 18.2 | 17 | 10 | 6 | 1 | 11 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.44 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 56 | 0 | 2 | 2 | 4.85 | .337 | 1.45 | 8.8 | 4.5 | 9.2 | 42.2 | 41 | 23 | 23 | 4 | 21 | 43 | 0 | 1 | 1 | 0 | 0 | 3 | 4 | 3.90 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 37 | 0 | 2 | 4 | 5.34 | .304 | 1.25 | 9.3 | 2.0 | 11.0 | 32.0 | 33 | 19 | 19 | 2 | 7 | 39 | 0 | 7 | 1 | 0 | 0 | 2 | 1 | 2.22 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 32 | 0 | 1 | 1 | 8.06 | .402 | 1.97 | 11.9 | 6.1 | 8.6 | 22.1 | 29 | 21 | 20 | 8 | 15 | 21 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 8.00 |