| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 28 | 28 | 12 | 10 | 4.71 | .314 | 1.31 | 8.5 | 3.3 | 7.8 | 185.1 | 174 | 103 | 97 | 26 | 68 | 161 | 4 | 0 | 0 | 0 | 13 | 12 | 3 | 4.38 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 80 | 27 | 27 | 8 | 13 | 5.00 | .312 | 1.33 | 9.0 | 3.0 | 8.1 | 172.2 | 172 | 101 | 96 | 22 | 58 | 155 | 3 | 0 | 0 | 1 | 12 | 5 | 12 | 3.96 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 72 | 27 | 27 | 8 | 14 | 5.68 | .321 | 1.40 | 9.7 | 2.9 | 4.7 | 198.0 | 214 | 130 | 125 | 36 | 63 | 104 | 6 | 0 | 0 | 0 | 8 | 4 | 6 | 5.33 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 27 | 27 | 10 | 13 | 5.17 | .308 | 1.31 | 9.3 | 2.5 | 6.8 | 184.2 | 190 | 107 | 106 | 20 | 52 | 139 | 2 | 0 | 0 | 1 | 8 | 5 | 7 | 3.83 |
| RP | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 75 | 0 | 5 | 6 | 3.61 | .267 | 1.08 | 7.0 | 2.8 | 8.4 | 99.2 | 77 | 46 | 40 | 16 | 31 | 92 | 0 | 13 | 6 | 0 | 0 | 1 | 3 | 4.21 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 46 | 0 | 3 | 2 | 3.67 | .305 | 1.30 | 7.1 | 4.7 | 9.8 | 56.1 | 44 | 26 | 23 | 8 | 29 | 61 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 4.29 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 56 | 28 | 0 | 2 | 3 | 4.75 | .341 | 1.55 | 9.9 | 4.2 | 8.1 | 30.1 | 33 | 22 | 16 | 2 | 14 | 27 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 3.47 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 21 | 0 | 0 | 3 | 5.87 | .320 | 1.38 | 7.3 | 5.2 | 8.1 | 38.1 | 31 | 25 | 25 | 3 | 22 | 34 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.05 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 9 | 1 | 0 | 1 | 5.57 | .323 | 1.38 | 9.4 | 3.0 | 6.0 | 21.0 | 22 | 13 | 13 | 3 | 7 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.67 |