| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 25 | 25 | 8 | 12 | 4.89 | .290 | 1.21 | 9.3 | 1.7 | 7.1 | 173.0 | 178 | 94 | 94 | 31 | 32 | 137 | 6 | 0 | 0 | 0 | 11 | 2 | 1 | 4.34 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 24 | 24 | 8 | 11 | 3.58 | .274 | 1.11 | 7.0 | 2.9 | 5.5 | 166.0 | 130 | 69 | 66 | 21 | 54 | 101 | 1 | 0 | 0 | 1 | 16 | 4 | 0 | 4.48 |
| SP | Johnson, R.Johnson, Randy † # >> | 41 | 2004 | L | 84 | 24 | 24 | 14 | 3 | 3.38 | .289 | 1.21 | 8.3 | 2.5 | 7.3 | 173.1 | 160 | 68 | 65 | 15 | 49 | 140 | 5 | 0 | 0 | 1 | 14 | 2 | 1 | 3.39 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 24 | 24 | 9 | 14 | 4.70 | .304 | 1.29 | 9.6 | 2.0 | 5.4 | 174.1 | 186 | 98 | 91 | 24 | 39 | 104 | 8 | 0 | 0 | 2 | 8 | 3 | 3 | 4.32 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 25 | 23 | 10 | 9 | 4.70 | .311 | 1.31 | 8.6 | 3.3 | 7.9 | 149.1 | 142 | 81 | 78 | 20 | 54 | 130 | 2 | 0 | 0 | 0 | 13 | 6 | 3 | 4.21 |
| RP | Uehara, K.Uehara, Koji $ >> | 38 | 2013 | R | 100 | 68 | 0 | 3 | 2 | 2.87 | .236 | 0.93 | 6.7 | 1.6 | 8.8 | 94.0 | 70 | 31 | 30 | 14 | 17 | 92 | 0 | 6 | 1 | 0 | 0 | 0 | 1 | 3.52 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 35 | 0 | 1 | 3 | 2.89 | .309 | 1.34 | 8.8 | 3.4 | 8.8 | 37.1 | 36 | 12 | 12 | 5 | 14 | 36 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 3.95 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 22 | 0 | 0 | 0 | 3.07 | .273 | 1.13 | 6.2 | 4.0 | 7.8 | 29.1 | 20 | 12 | 10 | 1 | 13 | 25 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 3.07 |