| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 93 | 19 | 19 | 8 | 7 | 5.36 | .313 | 1.36 | 8.9 | 3.4 | 7.7 | 102.1 | 101 | 65 | 61 | 10 | 38 | 87 | 0 | 0 | 0 | 0 | 6 | 1 | 3 | 3.72 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 19 | 19 | 9 | 6 | 3.61 | .292 | 1.22 | 8.6 | 2.5 | 4.9 | 124.2 | 118 | 51 | 50 | 9 | 34 | 67 | 0 | 0 | 0 | 0 | 14 | 2 | 3 | 3.73 |
| SP | Snell, B.Snell, Blake $ >> | 25 | 2018 | L | 80 | 18 | 18 | 10 | 4 | 4.13 | .284 | 1.18 | 7.4 | 3.3 | 6.8 | 102.1 | 84 | 48 | 47 | 16 | 37 | 77 | 0 | 0 | 0 | 0 | 9 | 1 | 6 | 4.65 |
| SP | Fernandez, J.Fernandez, Jose † # >> | 21 | 2013 | R | 76 | 18 | 18 | 13 | 2 | 3.13 | .262 | 1.06 | 6.1 | 3.5 | 7.5 | 123.2 | 83 | 46 | 43 | 6 | 48 | 102 | 2 | 0 | 0 | 2 | 12 | 1 | 0 | 3.17 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 16 | 16 | 8 | 4 | 5.12 | .337 | 1.49 | 10.3 | 3.2 | 7.0 | 91.1 | 104 | 54 | 52 | 12 | 32 | 71 | 1 | 0 | 0 | 0 | 6 | 3 | 4 | 4.31 |
| RP | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 50 | 0 | 7 | 1 | 2.61 | .257 | 1.01 | 5.4 | 3.8 | 8.6 | 72.1 | 43 | 21 | 21 | 2 | 30 | 69 | 0 | 9 | 2 | 0 | 0 | 2 | 4 | 2.78 |
| RP | Kuo, H.Kuo, Hong-Chih † >> | 29 | 2010 | L | 91 | 46 | 0 | 3 | 2 | 2.87 | .256 | 1.03 | 5.3 | 4.1 | 8.3 | 53.1 | 31 | 18 | 17 | 5 | 24 | 49 | 0 | 11 | 0 | 0 | 0 | 0 | 0 | 3.74 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 30 | 0 | 1 | 1 | 2.81 | .299 | 1.25 | 5.6 | 5.6 | 9.8 | 32.0 | 20 | 10 | 10 | 1 | 20 | 35 | 0 | 9 | 1 | 0 | 0 | 1 | 0 | 3.19 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 21 | 0 | 0 | 1 | 4.87 | .337 | 1.48 | 9.5 | 4.1 | 7.7 | 20.1 | 21 | 11 | 11 | 0 | 9 | 17 | 0 | 5 | 1 | 0 | 0 | 1 | 5 | 2.80 |
| RP | Radatz, D.Radatz, Dick >> | 27 | 1964 | R | 37 | 9 | 0 | 1 | 1 | 2.41 | .243 | 0.96 | 5.0 | 4.0 | 7.5 | 18.2 | 10 | 8 | 5 | 1 | 8 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.39 |