| SP | deGrom, J.deGrom, Jacob $ >> | 33 | 2021 | R | 100 | 31 | 31 | 12 | 9 | 3.39 | .274 | 1.10 | 7.2 | 2.7 | 9.6 | 209.2 | 168 | 86 | 79 | 27 | 62 | 223 | 0 | 0 | 0 | 0 | 21 | 7 | 0 | 3.54 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 30 | 30 | 10 | 13 | 4.61 | .312 | 1.35 | 9.4 | 2.8 | 9.3 | 195.1 | 204 | 112 | 100 | 32 | 60 | 201 | 1 | 0 | 0 | 1 | 17 | 2 | 1 | 4.03 |
| SP | Scott, M.Scott, Mike $$ >> | 31 | 1986 | R | 87 | 30 | 30 | 4 | 18 | 5.95 | .353 | 1.62 | 10.5 | 4.0 | 8.4 | 186.0 | 218 | 131 | 123 | 39 | 83 | 174 | 2 | 0 | 0 | 1 | 9 | 3 | 4 | 5.24 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 30 | 30 | 7 | 17 | 5.74 | .318 | 1.38 | 9.5 | 2.9 | 4.6 | 156.2 | 165 | 108 | 100 | 23 | 51 | 80 | 0 | 0 | 0 | 0 | 9 | 3 | 0 | 4.93 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 29 | 29 | 7 | 13 | 6.18 | .355 | 1.60 | 11.7 | 2.8 | 5.1 | 176.1 | 228 | 131 | 121 | 34 | 54 | 100 | 1 | 0 | 0 | 0 | 8 | 9 | 2 | 5.45 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 57 | 0 | 3 | 7 | 3.77 | .278 | 1.12 | 7.9 | 2.3 | 8.2 | 59.2 | 52 | 28 | 25 | 7 | 15 | 54 | 0 | 28 | 2 | 0 | 0 | 2 | 0 | 3.58 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 60 | 0 | 3 | 2 | 4.12 | .294 | 1.25 | 7.3 | 4.0 | 7.4 | 63.1 | 51 | 33 | 29 | 10 | 28 | 52 | 0 | 4 | 7 | 0 | 0 | 0 | 3 | 4.75 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 76 | 0 | 5 | 2 | 4.89 | .324 | 1.40 | 7.1 | 5.6 | 9.6 | 88.1 | 69 | 49 | 48 | 18 | 55 | 94 | 0 | 2 | 3 | 0 | 0 | 3 | 3 | 5.50 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 56 | 0 | 3 | 2 | 2.70 | .294 | 1.22 | 6.3 | 4.7 | 7.9 | 63.1 | 44 | 20 | 19 | 6 | 33 | 55 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 4.16 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 47 | 0 | 3 | 2 | 5.23 | .342 | 1.56 | 9.5 | 4.6 | 9.7 | 53.1 | 56 | 35 | 31 | 7 | 27 | 57 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.09 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 24 | 0 | 5 | 3 | 5.42 | .320 | 1.41 | 9.1 | 3.6 | 7.3 | 88.0 | 89 | 57 | 53 | 17 | 35 | 71 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.09 |