| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 97 | 28 | 28 | 8 | 13 | 4.35 | .312 | 1.29 | 8.9 | 2.7 | 7.9 | 213.1 | 211 | 114 | 103 | 29 | 65 | 188 | 7 | 0 | 0 | 0 | 13 | 14 | 6 | 4.12 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 29 | 29 | 12 | 14 | 4.67 | .315 | 1.36 | 9.6 | 2.6 | 4.1 | 206.1 | 220 | 115 | 107 | 24 | 60 | 94 | 5 | 0 | 0 | 1 | 13 | 5 | 4 | 4.55 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 29 | 29 | 6 | 19 | 5.39 | .341 | 1.53 | 9.9 | 3.9 | 6.4 | 210.1 | 231 | 134 | 126 | 29 | 90 | 150 | 10 | 0 | 0 | 1 | 10 | 5 | 6 | 4.72 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 29 | 29 | 10 | 7 | 4.60 | .332 | 1.47 | 9.1 | 4.1 | 4.1 | 178.0 | 179 | 101 | 91 | 29 | 82 | 82 | 0 | 0 | 0 | 0 | 13 | 4 | 1 | 5.65 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 28 | 28 | 11 | 7 | 4.96 | .352 | 1.59 | 10.4 | 3.9 | 4.5 | 181.1 | 209 | 108 | 100 | 22 | 79 | 90 | 1 | 0 | 0 | 0 | 14 | 7 | 3 | 5.01 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 98 | 73 | 0 | 5 | 5 | 3.77 | .272 | 1.10 | 6.2 | 3.8 | 10.0 | 112.1 | 77 | 49 | 47 | 17 | 47 | 124 | 0 | 8 | 3 | 0 | 0 | 2 | 0 | 4.07 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 59 | 0 | 7 | 6 | 3.42 | .314 | 1.33 | 8.1 | 4.0 | 9.7 | 68.1 | 61 | 28 | 26 | 6 | 30 | 73 | 0 | 7 | 1 | 0 | 0 | 3 | 4 | 3.46 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 36 | 0 | 2 | 3 | 2.41 | .317 | 1.37 | 8.3 | 4.0 | 8.6 | 41.0 | 38 | 14 | 11 | 5 | 18 | 39 | 0 | 7 | 3 | 0 | 0 | 1 | 0 | 4.07 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 24 | 0 | 0 | 1 | 3.61 | .324 | 1.39 | 8.2 | 4.4 | 9.2 | 47.1 | 43 | 20 | 19 | 7 | 23 | 48 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 4.49 |