| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 97 | 22 | 22 | 10 | 8 | 3.76 | .300 | 1.28 | 7.6 | 3.9 | 9.7 | 162.2 | 137 | 71 | 68 | 21 | 71 | 174 | 9 | 0 | 0 | 2 | 13 | 1 | 3 | 3.87 |
| SP | McKenzie, T.McKenzie, Triston >> | 22 | 2020 | R | 94 | 22 | 22 | 2 | 2 | 2.63 | .260 | 1.04 | 6.3 | 3.1 | 8.4 | 61.2 | 43 | 24 | 18 | 6 | 21 | 57 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.49 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 93 | 21 | 21 | 10 | 6 | 4.04 | .306 | 1.29 | 8.7 | 2.9 | 8.6 | 147.0 | 142 | 68 | 66 | 17 | 47 | 141 | 4 | 0 | 0 | 0 | 12 | 5 | 5 | 3.65 |
| SP | Siebert, S.Siebert, Sonny # >> | 31 | 1968 | R | 46 | 21 | 21 | 5 | 5 | 5.86 | .344 | 1.55 | 10.2 | 3.8 | 4.7 | 110.2 | 125 | 74 | 72 | 12 | 46 | 58 | 0 | 0 | 0 | 0 | 9 | 3 | 1 | 4.70 |
| RP | Manship, J.Manship, Jeff † >> | 30 | 2015 | R | 90 | 55 | 0 | 9 | 1 | 3.38 | .294 | 1.24 | 7.5 | 3.6 | 6.1 | 80.0 | 67 | 32 | 30 | 7 | 32 | 54 | 0 | 6 | 2 | 0 | 0 | 1 | 0 | 4.03 |
| RP | Perez, O.Perez, Oliver † >> | 37 | 2018 | L | 98 | 53 | 0 | 7 | 2 | 3.08 | .292 | 1.22 | 8.4 | 2.6 | 9.6 | 76.0 | 71 | 30 | 26 | 1 | 22 | 81 | 0 | 5 | 2 | 0 | 0 | 1 | 0 | 1.95 |
| RP | Bieber, S.Bieber, Shane >> | 25 | 2020 | R | 85 | 47 | 0 | 11 | 8 | 3.42 | .316 | 1.37 | 8.6 | 3.8 | 10.3 | 102.2 | 98 | 42 | 39 | 9 | 43 | 117 | 0 | 5 | 5 | 0 | 0 | 1 | 4 | 3.15 |
| RP | Plesac, Z.Plesac, Zach >> | 25 | 2020 | R | 78 | 39 | 0 | 5 | 3 | 3.56 | .273 | 1.11 | 8.5 | 1.6 | 9.3 | 68.1 | 64 | 28 | 27 | 11 | 12 | 70 | 0 | 7 | 3 | 0 | 0 | 1 | 0 | 3.62 |
| RP | Tomlin, J.Tomlin, Josh >> | 30 | 2015 | R | 65 | 22 | 0 | 4 | 3 | 5.67 | .346 | 1.56 | 9.8 | 4.4 | 8.2 | 33.1 | 36 | 21 | 21 | 8 | 16 | 30 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 5.88 |
| RP | Clippard, T.Clippard, Tyler >> | 34 | 2019 | R | 82 | 21 | 0 | 0 | 1 | 2.57 | .284 | 1.14 | 6.9 | 3.4 | 7.7 | 21.0 | 16 | 6 | 6 | 3 | 8 | 18 | 0 | 4 | 0 | 0 | 0 | 1 | 1 | 4.43 |
| RP | Harshman, J.Harshman, Jack >> | 32 | 1959 | L | 56 | 20 | 0 | 2 | 0 | 6.29 | .352 | 1.60 | 10.9 | 3.7 | 6.1 | 34.1 | 41 | 25 | 24 | 4 | 14 | 23 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.50 |