| SP | Jimenez, U.Jimenez, Ubaldo >> | 26 | 2010 | R | 51 | 29 | 29 | 12 | 9 | 4.48 | .331 | 1.46 | 9.3 | 3.9 | 6.1 | 182.2 | 188 | 100 | 91 | 13 | 79 | 124 | 1 | 0 | 0 | 1 | 15 | 4 | 10 | 3.93 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 36 | 28 | 28 | 7 | 10 | 6.73 | .358 | 1.63 | 10.5 | 4.2 | 8.0 | 125.2 | 146 | 101 | 94 | 22 | 59 | 111 | 0 | 0 | 0 | 0 | 2 | 5 | 6 | 5.05 |
| SP | Thomson, J.Thomson, John >> | 28 | 2001 | R | 40 | 28 | 28 | 0 | 8 | 5.09 | .327 | 1.44 | 9.9 | 3.2 | 7.3 | 70.2 | 77 | 40 | 40 | 13 | 25 | 57 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.90 |
| SP | Marquez, G.Marquez, German # >> | 23 | 2018 | R | 41 | 27 | 26 | 11 | 7 | 5.64 | .341 | 1.53 | 10.0 | 3.8 | 8.6 | 145.1 | 161 | 93 | 91 | 18 | 62 | 138 | 0 | 0 | 0 | 0 | 11 | 3 | 4 | 4.06 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 72 | 75 | 0 | 8 | 1 | 3.69 | .312 | 1.34 | 7.4 | 4.7 | 8.3 | 105.0 | 86 | 50 | 43 | 10 | 55 | 97 | 0 | 0 | 8 | 0 | 0 | 2 | 8 | 4.02 |
| RP | Miller, J.Miller, Justin >> | 28 | 2015 | R | 59 | 66 | 0 | 4 | 4 | 4.81 | .292 | 1.20 | 6.9 | 4.0 | 8.6 | 88.0 | 67 | 47 | 47 | 10 | 39 | 84 | 0 | 6 | 4 | 0 | 0 | 3 | 6 | 4.00 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 65 | 50 | 0 | 3 | 2 | 3.71 | .275 | 1.14 | 8.0 | 2.4 | 8.6 | 60.2 | 53 | 26 | 25 | 6 | 16 | 57 | 0 | 7 | 2 | 0 | 0 | 0 | 1 | 3.20 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 58 | 40 | 0 | 6 | 4 | 4.46 | .298 | 1.23 | 7.3 | 3.9 | 10.9 | 42.1 | 34 | 21 | 21 | 3 | 18 | 51 | 0 | 5 | 2 | 0 | 0 | 2 | 0 | 2.93 |
| RP | DeJean, M.DeJean, Mike >> | 35 | 2005 | R | 45 | 32 | 0 | 0 | 2 | 5.19 | .370 | 1.73 | 11.6 | 4.2 | 5.6 | 34.2 | 44 | 23 | 20 | 5 | 16 | 21 | 0 | 1 | 1 | 0 | 0 | 1 | 4 | 5.18 |
| SP | De La Rosa, J.De La Rosa, Jorge >> | 30 | 2011 | L | 43 | 57 | 0 | 15 | 3 | 4.82 | .339 | 1.52 | 8.6 | 5.1 | 5.3 | 134.1 | 128 | 78 | 72 | 14 | 76 | 79 | 0 | 1 | 0 | 0 | 0 | 3 | 11 | 4.95 |