| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 29 | 29 | 0 | 1 | 2.17 | .248 | 0.97 | 6.5 | 2.3 | 10.0 | 78.2 | 56 | 19 | 19 | 6 | 20 | 87 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 2.62 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 74 | 28 | 28 | 12 | 7 | 3.45 | .297 | 1.24 | 6.8 | 4.4 | 8.1 | 182.2 | 137 | 72 | 70 | 20 | 89 | 163 | 1 | 0 | 0 | 1 | 18 | 5 | 1 | 4.19 |
| SP | Verrett, L.Verrett, Logan >> | 25 | 2015 | R | 95 | 26 | 26 | 0 | 3 | 2.56 | .259 | 1.04 | 5.8 | 3.6 | 5.8 | 91.1 | 59 | 26 | 26 | 8 | 36 | 59 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.07 |
| SP | Lamabe, J.Lamabe, Jack >> | 31 | 1967 | R | 60 | 25 | 25 | 0 | 6 | 8.31 | .381 | 1.85 | 12.3 | 4.5 | 3.9 | 30.1 | 41 | 28 | 28 | 6 | 15 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6.23 |
| RP | Benitez, A.Benitez, Armando † >> | 27 | 1999 | R | 71 | 64 | 0 | 8 | 2 | 3.53 | .302 | 1.26 | 6.2 | 5.2 | 9.1 | 81.2 | 56 | 32 | 32 | 10 | 47 | 82 | 0 | 3 | 3 | 0 | 0 | 3 | 2 | 4.43 |
| RP | Wagner, B.Wagner, Billy >> | 37 | 2008 | L | 67 | 43 | 0 | 5 | 2 | 2.40 | .262 | 1.07 | 6.8 | 2.9 | 6.6 | 56.1 | 42 | 16 | 15 | 3 | 18 | 41 | 0 | 5 | 1 | 0 | 0 | 0 | 2 | 3.20 |
| RP | Carlyle, B.Carlyle, Buddy >> | 37 | 2014 | R | 52 | 37 | 0 | 6 | 3 | 5.00 | .328 | 1.44 | 9.4 | 3.6 | 8.0 | 45.0 | 47 | 26 | 25 | 5 | 18 | 40 | 0 | 4 | 3 | 0 | 0 | 1 | 0 | 3.93 |
| RP | McKeon, J.McKeon, Joel >> | 23 | 1986 | L | 50 | 29 | 0 | 1 | 0 | 1.41 | .281 | 1.15 | 6.4 | 4.0 | 3.3 | 38.1 | 27 | 6 | 6 | 2 | 17 | 14 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.37 |
| RP | Robles, H.Robles, Hansel >> | 24 | 2015 | R | 49 | 15 | 0 | 2 | 1 | 4.66 | .341 | 1.50 | 8.5 | 5.2 | 6.2 | 19.1 | 18 | 10 | 10 | 1 | 11 | 13 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.21 |
| SP | Scherzer, M.Scherzer, Max # >> | 38 | 2022 | R | 87 | 30 | 0 | 12 | 9 | 5.27 | .298 | 1.25 | 8.3 | 3.0 | 8.4 | 140.0 | 129 | 82 | 82 | 22 | 46 | 130 | 0 | 1 | 0 | 0 | 0 | 3 | 2 | 4.24 |
| SP | Martinez, P.Martinez, Pedro † >> | 34 | 2005 | R | 84 | 31 | 0 | 16 | 7 | 3.00 | .283 | 1.18 | 8.0 | 2.6 | 6.2 | 180.0 | 160 | 63 | 60 | 15 | 52 | 124 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 3.59 |
| SP | Sutherland, D.Sutherland, Darrell >> | 24 | 1965 | R | 66 | 27 | 3 | 3 | 1 | 3.31 | .307 | 1.33 | 8.7 | 3.3 | 4.4 | 35.1 | 34 | 14 | 13 | 5 | 13 | 17 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 5.00 |