| SP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 84 | 21 | 21 | 0 | 5 | 3.13 | .270 | 1.10 | 6.6 | 3.3 | 5.3 | 72.0 | 53 | 29 | 25 | 5 | 26 | 42 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 3.86 |
| SP | Ryan, N.Ryan, Nolan † # >> | 25 | 1972 | R | 64 | 22 | 22 | 14 | 7 | 2.56 | .279 | 1.15 | 6.2 | 4.2 | 8.1 | 172.1 | 119 | 51 | 49 | 12 | 80 | 154 | 11 | 0 | 0 | 3 | 17 | 1 | 5 | 3.53 |
| SP | Ohtani, S.Ohtani, Shohei >> | 28 | 2023 | R | 69 | 21 | 21 | 8 | 5 | 4.04 | .292 | 1.23 | 6.8 | 4.3 | 8.7 | 129.1 | 98 | 62 | 58 | 12 | 61 | 125 | 0 | 0 | 0 | 0 | 12 | 1 | 8 | 3.71 |
| SP | Richards, G.Richards, Garrett >> | 26 | 2014 | R | 52 | 21 | 21 | 4 | 12 | 4.79 | .307 | 1.31 | 8.3 | 3.5 | 7.0 | 135.1 | 125 | 74 | 72 | 18 | 52 | 105 | 1 | 0 | 0 | 0 | 11 | 3 | 11 | 4.40 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 47 | 20 | 20 | 6 | 7 | 5.49 | .331 | 1.48 | 10.1 | 3.3 | 4.5 | 121.1 | 136 | 78 | 74 | 18 | 44 | 60 | 1 | 0 | 0 | 0 | 8 | 0 | 3 | 5.03 |
| RP | Parker, B.Parker, Blake >> | 32 | 2017 | R | 88 | 51 | 0 | 3 | 0 | 2.64 | .283 | 1.13 | 7.2 | 3.0 | 8.5 | 71.2 | 57 | 21 | 21 | 6 | 24 | 67 | 0 | 1 | 1 | 0 | 0 | 4 | 5 | 3.39 |
| RP | Mayers, M.Mayers, Mike >> | 28 | 2020 | R | 76 | 54 | 0 | 1 | 4 | 3.98 | .285 | 1.20 | 6.6 | 4.1 | 8.4 | 61.0 | 45 | 27 | 27 | 7 | 28 | 57 | 0 | 8 | 3 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Frieri, E.Frieri, Ernesto >> | 26 | 2012 | R | 72 | 42 | 0 | 2 | 1 | 3.50 | .268 | 1.08 | 5.1 | 4.7 | 11.3 | 46.1 | 26 | 18 | 18 | 6 | 24 | 58 | 0 | 7 | 2 | 0 | 0 | 1 | 1 | 3.80 |
| RP | Petit, Y.Petit, Yusmeiro >> | 33 | 2017 | R | 41 | 18 | 0 | 4 | 1 | 3.04 | .237 | 0.85 | 5.5 | 2.3 | 9.0 | 23.2 | 14 | 8 | 8 | 4 | 6 | 23 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.30 |
| RP | Andriese, M.Andriese, Matt >> | 30 | 2020 | R | 48 | 10 | 0 | 1 | 1 | 1.56 | .246 | 0.98 | 5.8 | 3.2 | 4.8 | 17.1 | 11 | 3 | 3 | 1 | 6 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.76 |