| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 89 | 33 | 33 | 16 | 12 | 3.98 | .317 | 1.34 | 8.7 | 3.4 | 10.0 | 224.0 | 217 | 104 | 99 | 36 | 84 | 250 | 1 | 0 | 0 | 0 | 19 | 11 | 3 | 4.13 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 74 | 31 | 31 | 4 | 12 | 5.49 | .339 | 1.50 | 9.7 | 3.9 | 9.3 | 134.1 | 144 | 86 | 82 | 23 | 58 | 139 | 0 | 0 | 0 | 0 | 2 | 5 | 3 | 4.57 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 32 | 32 | 4 | 14 | 5.44 | .341 | 1.50 | 8.3 | 5.2 | 9.4 | 177.0 | 164 | 113 | 107 | 23 | 102 | 185 | 0 | 0 | 0 | 0 | 9 | 9 | 5 | 4.48 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 62 | 31 | 31 | 8 | 13 | 5.55 | .326 | 1.44 | 10.1 | 2.9 | 6.9 | 183.1 | 206 | 115 | 113 | 43 | 58 | 141 | 1 | 0 | 0 | 0 | 13 | 2 | 3 | 5.50 |
| CL | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 94 | 64 | 0 | 4 | 11 | 3.63 | .301 | 1.25 | 8.5 | 2.8 | 10.5 | 72.0 | 68 | 30 | 29 | 9 | 22 | 84 | 0 | 31 | 5 | 0 | 0 | 3 | 1 | 3.33 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 87 | 53 | 0 | 3 | 2 | 3.24 | .271 | 1.08 | 6.1 | 3.7 | 8.6 | 80.2 | 54 | 29 | 29 | 9 | 33 | 76 | 0 | 3 | 7 | 0 | 0 | 3 | 0 | 3.91 |
| RP | Harvey, B.Harvey, Bryan # >> | 28 | 1991 | R | 63 | 81 | 0 | 4 | 3 | 6.86 | .337 | 1.52 | 9.9 | 3.9 | 9.8 | 84.0 | 92 | 64 | 64 | 19 | 36 | 91 | 0 | 1 | 3 | 0 | 0 | 0 | 2 | 5.06 |
| RP | Guardado, E.Guardado, Eddie >> | 33 | 2003 | L | 23 | 53 | 0 | 2 | 4 | 4.55 | .311 | 1.35 | 8.4 | 3.8 | 7.2 | 61.1 | 57 | 31 | 31 | 15 | 26 | 49 | 0 | 1 | 1 | 0 | 0 | 0 | 5 | 5.87 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 59 | 26 | 1 | 5 | 2 | 4.87 | .329 | 1.44 | 9.9 | 3.0 | 5.9 | 116.1 | 128 | 66 | 63 | 19 | 39 | 76 | 0 | 0 | 0 | 0 | 0 | 4 | 1 | 4.93 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 21 | 1981 | L | 60 | 13 | 0 | 2 | 3 | 6.85 | .350 | 1.57 | 11.0 | 3.3 | 9.0 | 22.1 | 27 | 17 | 17 | 8 | 8 | 22 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 6.95 |