| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 34 | 34 | 7 | 14 | 4.53 | .312 | 1.33 | 8.4 | 3.6 | 9.5 | 210.2 | 197 | 112 | 106 | 32 | 83 | 222 | 0 | 0 | 0 | 0 | 18 | 7 | 5 | 4.15 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 33 | 33 | 10 | 14 | 5.61 | .331 | 1.44 | 10.2 | 2.8 | 9.7 | 199.0 | 225 | 129 | 124 | 43 | 61 | 214 | 0 | 0 | 0 | 0 | 13 | 9 | 3 | 4.71 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 78 | 32 | 32 | 9 | 14 | 5.52 | .326 | 1.39 | 9.4 | 3.1 | 6.7 | 187.2 | 196 | 119 | 115 | 26 | 65 | 139 | 0 | 0 | 0 | 0 | 17 | 11 | 7 | 4.54 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 32 | 32 | 9 | 13 | 5.80 | .338 | 1.52 | 10.2 | 3.4 | 7.0 | 175.1 | 199 | 123 | 113 | 31 | 67 | 136 | 1 | 0 | 0 | 0 | 13 | 3 | 3 | 4.95 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 67 | 31 | 31 | 11 | 10 | 4.26 | .333 | 1.47 | 10.0 | 3.2 | 5.9 | 209.0 | 233 | 100 | 99 | 26 | 75 | 138 | 4 | 0 | 0 | 1 | 15 | 5 | 0 | 4.44 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 69 | 0 | 4 | 6 | 3.60 | .314 | 1.33 | 8.7 | 3.2 | 8.5 | 70.0 | 68 | 28 | 28 | 6 | 25 | 66 | 0 | 36 | 10 | 0 | 0 | 3 | 0 | 3.43 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 75 | 85 | 0 | 6 | 2 | 3.16 | .268 | 1.09 | 7.3 | 2.6 | 9.7 | 62.2 | 50 | 22 | 22 | 8 | 18 | 67 | 0 | 0 | 1 | 0 | 0 | 1 | 4 | 3.44 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 64 | 71 | 0 | 1 | 2 | 3.75 | .273 | 1.10 | 6.4 | 3.6 | 6.6 | 81.2 | 58 | 35 | 34 | 7 | 32 | 59 | 0 | 3 | 2 | 0 | 0 | 2 | 1 | 3.93 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 63 | 51 | 0 | 6 | 3 | 4.08 | .298 | 1.27 | 7.4 | 4.1 | 8.8 | 57.1 | 47 | 26 | 26 | 10 | 26 | 56 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 4.68 |