| SP | deGrom, J.deGrom, Jacob $$ >> | 33 | 2021 | R | 100 | 32 | 32 | 12 | 13 | 3.57 | .266 | 1.09 | 7.6 | 2.2 | 8.3 | 209.1 | 177 | 85 | 83 | 26 | 51 | 192 | 2 | 0 | 0 | 0 | 21 | 0 | 0 | 3.51 |
| SP | Gibson, B.Gibson, Bob $$ >> | 33 | 1968 | R | 92 | 31 | 31 | 7 | 17 | 5.68 | .337 | 1.51 | 9.9 | 3.7 | 5.7 | 191.2 | 211 | 125 | 121 | 30 | 78 | 120 | 3 | 0 | 0 | 0 | 12 | 3 | 4 | 5.06 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 30 | 30 | 10 | 11 | 4.95 | .333 | 1.46 | 10.2 | 2.9 | 4.5 | 191.0 | 216 | 111 | 105 | 24 | 62 | 96 | 6 | 0 | 0 | 0 | 14 | 8 | 3 | 4.73 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 64 | 0 | 3 | 5 | 3.20 | .298 | 1.25 | 6.9 | 4.4 | 10.2 | 76.0 | 58 | 27 | 27 | 5 | 37 | 86 | 0 | 35 | 3 | 0 | 0 | 2 | 5 | 3.13 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 65 | 0 | 2 | 5 | 5.14 | .327 | 1.40 | 8.4 | 4.1 | 8.1 | 63.0 | 59 | 36 | 36 | 9 | 29 | 57 | 0 | 7 | 6 | 0 | 0 | 4 | 0 | 4.62 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 67 | 0 | 6 | 5 | 4.03 | .296 | 1.25 | 6.3 | 5.0 | 8.8 | 87.0 | 61 | 41 | 39 | 8 | 48 | 85 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 3.93 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 54 | 0 | 5 | 1 | 1.74 | .228 | 0.85 | 4.5 | 3.2 | 7.4 | 62.0 | 31 | 13 | 12 | 4 | 22 | 51 | 0 | 1 | 0 | 0 | 0 | 2 | 6 | 3.35 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 40 | 0 | 0 | 4 | 7.42 | .340 | 1.52 | 10.1 | 3.6 | 5.9 | 47.1 | 53 | 41 | 39 | 8 | 19 | 31 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 5.17 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 26 | 0 | 3 | 2 | 3.72 | .303 | 1.29 | 8.4 | 3.3 | 4.5 | 111.1 | 103 | 49 | 46 | 11 | 41 | 56 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 4.41 |