| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 32 | 32 | 18 | 6 | 2.95 | .274 | 1.12 | 8.1 | 2.0 | 8.7 | 234.2 | 210 | 80 | 77 | 22 | 53 | 227 | 6 | 0 | 0 | 2 | 24 | 3 | 3 | 3.00 |
| SP | Kluber, C.Kluber, Corey $ >> | 31 | 2017 | R | 89 | 31 | 31 | 13 | 10 | 4.76 | .317 | 1.38 | 10.0 | 2.4 | 7.9 | 189.0 | 209 | 106 | 100 | 29 | 51 | 166 | 3 | 0 | 0 | 1 | 15 | 3 | 3 | 4.10 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 31 | 31 | 15 | 10 | 3.55 | .268 | 1.07 | 7.9 | 1.7 | 8.5 | 218.0 | 192 | 87 | 86 | 29 | 42 | 206 | 6 | 0 | 0 | 1 | 22 | 5 | 0 | 3.49 |
| SP | Fernandez, S.Fernandez, Sid $ >> | 23 | 1985 | L | 49 | 29 | 29 | 14 | 10 | 3.82 | .302 | 1.29 | 6.9 | 4.8 | 7.3 | 186.1 | 142 | 80 | 79 | 19 | 99 | 151 | 2 | 0 | 0 | 0 | 17 | 1 | 3 | 4.32 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 31 | 29 | 13 | 9 | 3.27 | .286 | 1.18 | 7.2 | 3.5 | 7.2 | 189.2 | 151 | 70 | 69 | 21 | 73 | 152 | 1 | 0 | 0 | 1 | 20 | 4 | 1 | 4.06 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 45 | 0 | 4 | 5 | 3.02 | .277 | 1.13 | 7.6 | 2.7 | 11.9 | 56.2 | 47 | 21 | 19 | 7 | 17 | 74 | 0 | 3 | 4 | 0 | 0 | 1 | 1 | 2.95 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 37 | 0 | 2 | 1 | 4.50 | .302 | 1.30 | 8.3 | 3.4 | 7.9 | 40.0 | 37 | 20 | 20 | 6 | 15 | 35 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 4.33 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 23 | 0 | 1 | 0 | 4.03 | .281 | 1.17 | 5.9 | 4.7 | 9.6 | 29.0 | 19 | 13 | 13 | 3 | 15 | 31 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.76 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 30 | 0 | 1 | 0 | 2.51 | .248 | 0.93 | 6.5 | 2.0 | 7.9 | 32.1 | 23 | 9 | 9 | 7 | 7 | 28 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 4.94 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 8 | 2 | 2 | 2 | 8.35 | .433 | 2.29 | 11.0 | 10.0 | 7.5 | 18.1 | 22 | 19 | 17 | 3 | 20 | 15 | 0 | 0 | 1 | 0 | 1 | 0 | 3 | 6.83 |