| SP | Koufax, S.Koufax, Sandy $ >> | 30 | 1965 | L | 98 | 32 | 32 | 15 | 11 | 4.08 | .317 | 1.38 | 9.0 | 3.4 | 8.8 | 209.1 | 209 | 105 | 95 | 34 | 80 | 205 | 8 | 0 | 0 | 2 | 16 | 2 | 5 | 4.33 |
| SP | Mathewson, C.Mathewson, Christy † >> | 28 | 1908 | R | 82 | 31 | 31 | 16 | 8 | 2.95 | .274 | 1.09 | 8.0 | 1.8 | 5.3 | 229.0 | 204 | 80 | 75 | 16 | 46 | 136 | 9 | 0 | 0 | 1 | 23 | 9 | 1 | 3.44 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 31 | 31 | 17 | 5 | 3.96 | .296 | 1.24 | 8.1 | 3.1 | 5.4 | 195.1 | 175 | 89 | 86 | 10 | 67 | 117 | 0 | 0 | 0 | 0 | 18 | 4 | 1 | 3.56 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 31 | 31 | 10 | 10 | 6.23 | .356 | 1.63 | 11.7 | 3.0 | 4.7 | 170.1 | 221 | 127 | 118 | 26 | 57 | 88 | 6 | 0 | 0 | 1 | 8 | 4 | 5 | 5.03 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 29 | 29 | 7 | 13 | 5.42 | .352 | 1.60 | 10.8 | 3.7 | 5.7 | 162.2 | 194 | 108 | 98 | 23 | 66 | 102 | 1 | 0 | 0 | 1 | 12 | 5 | 9 | 4.90 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 78 | 0 | 2 | 2 | 4.66 | .315 | 1.36 | 7.8 | 4.5 | 8.0 | 46.1 | 40 | 24 | 24 | 5 | 23 | 41 | 0 | 5 | 2 | 0 | 0 | 1 | 4 | 4.20 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 59 | 0 | 6 | 0 | 2.27 | .256 | 1.01 | 5.9 | 3.3 | 9.6 | 43.2 | 28 | 11 | 11 | 2 | 16 | 46 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 2.65 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 41 | 0 | 3 | 3 | 4.95 | .341 | 1.55 | 9.2 | 4.7 | 7.7 | 40.0 | 41 | 23 | 22 | 7 | 21 | 34 | 0 | 5 | 0 | 0 | 0 | 0 | 2 | 5.15 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 13 | 0 | 5 | 1 | 5.96 | .339 | 1.54 | 8.8 | 5.1 | 5.6 | 51.1 | 50 | 41 | 34 | 5 | 29 | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 4.73 |