| SP | Richard, J.Richard, J.R. $ >> | 30 | 1980 | R | 90 | 32 | 32 | 14 | 10 | 4.30 | .307 | 1.31 | 7.9 | 3.9 | 8.1 | 199.0 | 174 | 101 | 95 | 26 | 86 | 178 | 2 | 0 | 0 | 0 | 17 | 4 | 4 | 4.27 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 31 | 31 | 8 | 11 | 4.13 | .316 | 1.38 | 9.8 | 2.6 | 6.7 | 196.1 | 213 | 93 | 90 | 18 | 57 | 146 | 4 | 0 | 0 | 2 | 18 | 2 | 9 | 3.61 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 31 | 31 | 15 | 8 | 3.62 | .279 | 1.14 | 7.5 | 2.7 | 4.0 | 214.0 | 179 | 88 | 86 | 19 | 65 | 94 | 6 | 0 | 0 | 1 | 19 | 5 | 0 | 4.26 |
| RP | Miller, A.Miller, Andrew † >> | 29 | 2014 | L | 88 | 81 | 0 | 10 | 0 | 1.32 | .232 | 0.89 | 4.7 | 3.3 | 9.4 | 109.0 | 57 | 18 | 16 | 7 | 40 | 114 | 0 | 0 | 2 | 0 | 0 | 2 | 3 | 2.90 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 67 | 0 | 4 | 2 | 4.56 | .306 | 1.28 | 7.1 | 4.4 | 7.3 | 75.0 | 59 | 40 | 38 | 8 | 37 | 61 | 0 | 3 | 0 | 0 | 0 | 3 | 0 | 4.36 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 55 | 0 | 5 | 2 | 4.43 | .344 | 1.56 | 7.6 | 6.4 | 9.4 | 63.0 | 53 | 31 | 31 | 4 | 45 | 66 | 0 | 1 | 2 | 0 | 0 | 1 | 5 | 3.92 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 47 | 0 | 1 | 1 | 1.84 | .273 | 1.09 | 7.4 | 2.5 | 8.8 | 58.2 | 48 | 12 | 12 | 4 | 16 | 57 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 2.86 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 19 | 0 | 3 | 2 | 3.82 | .316 | 1.33 | 7.7 | 4.4 | 4.1 | 35.1 | 30 | 16 | 15 | 5 | 17 | 16 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 5.57 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 81 | 0 | 5 | 8 | 3.26 | .270 | 1.10 | 7.6 | 2.3 | 8.3 | 85.2 | 72 | 32 | 31 | 13 | 22 | 78 | 0 | 41 | 4 | 0 | 0 | 1 | 2 | 3.96 |