| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 29 | 29 | 12 | 11 | 3.49 | .298 | 1.26 | 8.4 | 2.8 | 5.1 | 196.0 | 184 | 80 | 76 | 15 | 62 | 112 | 6 | 0 | 0 | 1 | 21 | 4 | 3 | 3.86 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 26 | 26 | 11 | 6 | 3.99 | .312 | 1.33 | 7.7 | 4.3 | 4.2 | 169.1 | 145 | 79 | 75 | 14 | 81 | 79 | 3 | 0 | 0 | 1 | 14 | 4 | 2 | 4.65 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 27 | 27 | 11 | 9 | 4.38 | .301 | 1.28 | 7.9 | 3.7 | 8.1 | 152.0 | 133 | 75 | 74 | 23 | 62 | 136 | 0 | 0 | 0 | 0 | 16 | 1 | 4 | 4.42 |
| SP | McDowell, S.McDowell, Sam >> | 26 | 1968 | L | 46 | 27 | 26 | 9 | 10 | 4.54 | .334 | 1.48 | 8.9 | 4.5 | 8.0 | 162.2 | 160 | 89 | 82 | 16 | 81 | 144 | 1 | 0 | 0 | 0 | 12 | 4 | 4 | 4.08 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 76 | 0 | 8 | 2 | 3.59 | .263 | 1.04 | 5.8 | 3.6 | 8.3 | 95.1 | 61 | 39 | 38 | 7 | 38 | 88 | 0 | 8 | 1 | 0 | 0 | 3 | 9 | 3.40 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 62 | 0 | 4 | 2 | 2.35 | .252 | 1.01 | 7.7 | 1.5 | 6.5 | 80.1 | 68 | 21 | 21 | 8 | 13 | 58 | 0 | 9 | 2 | 0 | 0 | 0 | 0 | 3.34 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 47 | 0 | 5 | 2 | 3.71 | .273 | 1.13 | 8.3 | 1.9 | 6.4 | 63.0 | 58 | 27 | 26 | 3 | 13 | 45 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 2.81 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 80 | 33 | 0 | 2 | 1 | 3.69 | .282 | 1.18 | 7.4 | 3.2 | 8.5 | 39.0 | 32 | 16 | 16 | 4 | 14 | 37 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 3.51 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 28 | 0 | 1 | 3 | 3.22 | .301 | 1.29 | 7.0 | 4.8 | 9.0 | 36.1 | 28 | 13 | 13 | 2 | 19 | 36 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.31 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 10 | 1 | 1 | 3 | 4.95 | .311 | 1.31 | 7.7 | 4.2 | 3.8 | 43.2 | 37 | 27 | 24 | 7 | 20 | 18 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 5.81 |