| SP | Verlander, J.Verlander, Justin † >> | 36 | 2019 | R | 99 | 36 | 36 | 18 | 11 | 3.43 | .292 | 1.22 | 8.0 | 3.0 | 7.4 | 241.1 | 214 | 97 | 92 | 32 | 81 | 199 | 2 | 0 | 0 | 1 | 25 | 4 | 3 | 4.13 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 91 | 33 | 33 | 10 | 14 | 5.07 | .308 | 1.31 | 8.7 | 3.1 | 9.5 | 193.1 | 186 | 110 | 109 | 21 | 67 | 204 | 1 | 0 | 0 | 1 | 15 | 5 | 1 | 3.42 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 31 | 31 | 14 | 7 | 4.33 | .301 | 1.28 | 8.7 | 2.8 | 4.6 | 189.0 | 183 | 99 | 91 | 23 | 59 | 96 | 6 | 0 | 0 | 1 | 14 | 2 | 1 | 4.53 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 98 | 0 | 7 | 1 | 2.98 | .245 | 0.96 | 5.3 | 3.3 | 9.5 | 105.2 | 62 | 36 | 35 | 12 | 39 | 111 | 0 | 3 | 2 | 0 | 0 | 2 | 4 | 3.54 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 93 | 0 | 2 | 3 | 3.23 | .256 | 0.99 | 5.7 | 3.2 | 7.3 | 92.0 | 58 | 33 | 33 | 11 | 33 | 75 | 0 | 6 | 2 | 0 | 0 | 4 | 0 | 4.13 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 79 | 0 | 5 | 5 | 3.58 | .269 | 1.10 | 6.0 | 4.0 | 8.3 | 65.1 | 43 | 26 | 26 | 6 | 29 | 60 | 0 | 10 | 1 | 0 | 0 | 0 | 2 | 3.69 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 81 | 0 | 2 | 4 | 3.99 | .302 | 1.26 | 7.8 | 3.7 | 8.2 | 58.2 | 50 | 27 | 26 | 8 | 24 | 53 | 0 | 6 | 4 | 0 | 0 | 2 | 6 | 4.31 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 49 | 0 | 3 | 1 | 3.61 | .279 | 1.10 | 6.1 | 3.8 | 9.0 | 47.1 | 32 | 19 | 19 | 8 | 20 | 47 | 0 | 5 | 0 | 0 | 0 | 3 | 1 | 4.68 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 3 | 2 | 2 | 1 | 5.06 | .324 | 1.44 | 7.9 | 5.1 | 4.5 | 16.0 | 14 | 9 | 9 | 3 | 9 | 8 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 6.13 |