| SP | McNally, D.McNally, Dave † >> | 26 | 1968 | L | 96 | 32 | 32 | 16 | 14 | 4.14 | .290 | 1.19 | 7.8 | 2.9 | 5.8 | 222.0 | 193 | 105 | 102 | 24 | 72 | 144 | 11 | 0 | 0 | 3 | 16 | 7 | 0 | 4.18 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 31 | 31 | 11 | 14 | 5.00 | .332 | 1.47 | 10.2 | 3.1 | 5.0 | 225.0 | 254 | 140 | 125 | 27 | 77 | 126 | 6 | 0 | 0 | 0 | 9 | 5 | 7 | 4.53 |
| SP | Krause, H.Krause, Harry # >> | 21 | 1909 | L | 72 | 30 | 30 | 7 | 16 | 4.65 | .299 | 1.26 | 8.3 | 3.1 | 5.6 | 186.0 | 171 | 99 | 96 | 27 | 64 | 116 | 2 | 0 | 0 | 0 | 14 | 3 | 0 | 4.72 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 30 | 30 | 9 | 13 | 4.65 | .311 | 1.33 | 9.5 | 2.5 | 4.8 | 205.0 | 216 | 116 | 106 | 23 | 56 | 110 | 11 | 0 | 0 | 1 | 15 | 5 | 3 | 4.28 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 30 | 30 | 8 | 10 | 4.84 | .313 | 1.35 | 8.1 | 4.1 | 3.8 | 178.2 | 160 | 96 | 96 | 24 | 82 | 75 | 0 | 0 | 0 | 0 | 15 | 2 | 4 | 5.33 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 80 | 0 | 7 | 4 | 2.56 | .262 | 1.06 | 7.5 | 2.1 | 9.7 | 105.1 | 87 | 32 | 30 | 11 | 25 | 113 | 0 | 5 | 3 | 0 | 0 | 0 | 1 | 2.92 |
| RP | Rhodes, A.Rhodes, Arthur # >> | 32 | 2001 | L | 64 | 68 | 0 | 3 | 6 | 4.96 | .298 | 1.25 | 7.4 | 3.9 | 8.9 | 81.2 | 67 | 46 | 45 | 13 | 35 | 80 | 0 | 6 | 5 | 0 | 0 | 2 | 2 | 4.48 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 38 | 0 | 3 | 1 | 5.13 | .326 | 1.45 | 10.7 | 2.5 | 9.0 | 54.1 | 64 | 36 | 31 | 10 | 15 | 54 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.24 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 48 | 1 | 0 | 0 | 0 | 0.00 | .250 | 1.00 | 9.0 | 0.0 | 9.0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 55 | 1 | 0 | 0 | 0 | 40.50 | .692 | 6.75 | 45.0 | 36.0 | 9.0 | 1.1 | 5 | 6 | 6 | 1 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 26.00 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 10 | 0 | 1 | 1 | 7.11 | .345 | 1.53 | 9.5 | 4.3 | 6.6 | 19.0 | 20 | 15 | 15 | 1 | 9 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.79 |