| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 22 | 22 | 9 | 9 | 3.69 | .270 | 1.09 | 7.0 | 2.8 | 8.0 | 151.1 | 118 | 63 | 62 | 20 | 47 | 134 | 2 | 0 | 0 | 1 | 13 | 3 | 2 | 3.94 |
| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 89 | 21 | 21 | 11 | 5 | 3.15 | .279 | 1.12 | 8.0 | 2.1 | 5.5 | 168.1 | 150 | 63 | 59 | 11 | 39 | 102 | 8 | 0 | 0 | 2 | 14 | 6 | 2 | 3.44 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 21 | 21 | 9 | 5 | 4.82 | .329 | 1.46 | 7.9 | 5.3 | 7.6 | 134.1 | 117 | 78 | 72 | 7 | 79 | 113 | 0 | 0 | 0 | 0 | 7 | 2 | 2 | 3.81 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 20 | 20 | 7 | 5 | 5.23 | .330 | 1.47 | 9.4 | 4.0 | 4.3 | 118.2 | 123 | 77 | 69 | 11 | 52 | 57 | 0 | 0 | 0 | 0 | 9 | 0 | 1 | 4.57 |
| RP | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 93 | 58 | 0 | 5 | 4 | 3.78 | .296 | 1.25 | 6.2 | 5.0 | 9.1 | 88.0 | 61 | 39 | 37 | 11 | 49 | 89 | 0 | 8 | 3 | 0 | 0 | 1 | 0 | 4.31 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 50 | 0 | 3 | 3 | 5.54 | .317 | 1.39 | 8.5 | 4.1 | 8.1 | 50.1 | 47 | 35 | 31 | 11 | 23 | 45 | 0 | 7 | 4 | 0 | 0 | 0 | 1 | 5.44 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 30 | 0 | 4 | 2 | 3.24 | .296 | 1.26 | 7.1 | 4.4 | 7.9 | 33.1 | 26 | 12 | 12 | 3 | 16 | 29 | 0 | 5 | 4 | 0 | 0 | 0 | 0 | 3.88 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 46 | 8 | 0 | 3 | 3 | 6.50 | .361 | 1.69 | 10.0 | 5.3 | 9.0 | 36.0 | 40 | 27 | 26 | 7 | 21 | 36 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.28 |