| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 28 | 28 | 6 | 12 | 5.24 | .329 | 1.46 | 10.3 | 2.9 | 4.6 | 147.2 | 168 | 93 | 86 | 23 | 47 | 75 | 0 | 0 | 0 | 0 | 7 | 2 | 2 | 5.01 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 27 | 27 | 12 | 12 | 3.74 | .290 | 1.20 | 8.0 | 2.8 | 6.0 | 209.1 | 185 | 94 | 87 | 17 | 66 | 140 | 13 | 0 | 0 | 3 | 14 | 6 | 5 | 3.75 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 68 | 0 | 1 | 3 | 2.45 | .252 | 1.00 | 6.9 | 2.1 | 9.5 | 99.0 | 76 | 29 | 27 | 4 | 23 | 104 | 0 | 4 | 0 | 0 | 0 | 1 | 1 | 2.15 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 70 | 0 | 4 | 7 | 4.14 | .297 | 1.22 | 8.8 | 2.3 | 7.5 | 95.2 | 93 | 47 | 44 | 13 | 24 | 79 | 0 | 6 | 3 | 0 | 0 | 4 | 2 | 4.00 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 74 | 58 | 0 | 5 | 2 | 3.27 | .313 | 1.36 | 6.7 | 5.6 | 10.6 | 66.0 | 49 | 26 | 24 | 3 | 41 | 78 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 3.09 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 48 | 0 | 4 | 4 | 3.05 | .264 | 1.06 | 5.5 | 4.0 | 9.4 | 65.0 | 40 | 23 | 22 | 9 | 29 | 68 | 0 | 4 | 3 | 0 | 0 | 1 | 3 | 4.09 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 3 | 0 | 0 | 0 | 3.86 | .391 | 1.71 | 9.0 | 9.0 | 0.0 | 4.2 | 4 | 2 | 2 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 10.00 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 31 | 0 | 2 | 4 | 6.30 | .395 | 1.86 | 12.2 | 4.5 | 4.3 | 50.0 | 68 | 37 | 35 | 6 | 25 | 24 | 0 | 3 | 0 | 0 | 0 | 5 | 1 | 5.40 |