| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 29 | 29 | 11 | 14 | 3.63 | .302 | 1.27 | 8.5 | 3.0 | 8.4 | 198.1 | 186 | 83 | 80 | 18 | 66 | 184 | 3 | 0 | 0 | 1 | 20 | 5 | 3 | 3.40 |
| SP | Alexander, P.Alexander, Pete † # >> | 28 | 1915 | R | 88 | 28 | 28 | 13 | 11 | 3.04 | .235 | 0.91 | 6.8 | 1.4 | 5.3 | 216.1 | 164 | 77 | 73 | 19 | 33 | 126 | 16 | 0 | 0 | 7 | 17 | 2 | 0 | 3.46 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 27 | 27 | 7 | 12 | 4.41 | .311 | 1.34 | 8.8 | 3.3 | 8.2 | 159.1 | 155 | 80 | 78 | 19 | 59 | 144 | 0 | 0 | 0 | 0 | 15 | 2 | 4 | 3.89 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 26 | 26 | 8 | 17 | 4.53 | .319 | 1.40 | 8.6 | 4.0 | 5.7 | 173.0 | 166 | 92 | 87 | 24 | 76 | 109 | 6 | 0 | 0 | 2 | 12 | 1 | 2 | 4.88 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 63 | 0 | 1 | 2 | 2.44 | .249 | 0.97 | 5.4 | 3.4 | 9.5 | 77.1 | 46 | 21 | 21 | 5 | 29 | 81 | 0 | 6 | 3 | 0 | 0 | 2 | 0 | 2.95 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 52 | 0 | 3 | 4 | 2.55 | .291 | 1.20 | 6.3 | 4.5 | 8.7 | 60.0 | 42 | 20 | 17 | 1 | 30 | 58 | 0 | 5 | 3 | 0 | 0 | 2 | 0 | 2.88 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 4 | 1 | 0 | 1 | 1.00 | .289 | 1.22 | 8.0 | 3.0 | 4.0 | 9.0 | 8 | 5 | 1 | 0 | 3 | 4 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 3.11 |