| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 28 | 28 | 19 | 6 | 3.35 | .274 | 1.11 | 8.4 | 1.6 | 7.9 | 201.1 | 188 | 75 | 75 | 20 | 36 | 177 | 4 | 0 | 0 | 0 | 18 | 4 | 3 | 3.13 |
| SP | Richard, J.Richard, J.R. † >> | 30 | 1980 | R | 90 | 28 | 28 | 16 | 7 | 4.39 | .321 | 1.41 | 8.2 | 4.5 | 8.4 | 182.2 | 166 | 89 | 89 | 14 | 91 | 169 | 0 | 0 | 0 | 0 | 15 | 2 | 5 | 3.68 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 27 | 27 | 4 | 17 | 7.66 | .376 | 1.80 | 12.2 | 4.0 | 4.2 | 155.0 | 210 | 135 | 132 | 29 | 69 | 73 | 2 | 0 | 0 | 1 | 4 | 1 | 3 | 5.85 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 63 | 0 | 2 | 1 | 3.53 | .299 | 1.27 | 6.8 | 4.6 | 9.3 | 79.0 | 60 | 33 | 31 | 5 | 40 | 82 | 0 | 1 | 1 | 0 | 0 | 1 | 9 | 3.30 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 52 | 0 | 3 | 3 | 5.88 | .351 | 1.59 | 8.5 | 5.9 | 7.9 | 59.2 | 56 | 40 | 39 | 9 | 39 | 52 | 0 | 2 | 2 | 0 | 0 | 2 | 3 | 5.31 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 16 | 0 | 1 | 2 | 5.22 | .348 | 1.57 | 8.1 | 6.2 | 5.6 | 29.1 | 26 | 17 | 17 | 4 | 20 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.72 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 60 | 0 | 2 | 3 | 2.64 | .279 | 1.14 | 8.3 | 2.1 | 9.1 | 64.2 | 59 | 21 | 19 | 2 | 15 | 65 | 0 | 31 | 2 | 0 | 0 | 1 | 0 | 2.13 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 41 | 0 | 2 | 1 | 5.20 | .351 | 1.60 | 9.2 | 5.2 | 8.2 | 45.0 | 46 | 30 | 26 | 11 | 26 | 41 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 6.16 |