| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 29 | 29 | 8 | 12 | 3.92 | .299 | 1.25 | 8.1 | 3.1 | 7.2 | 200.0 | 181 | 93 | 87 | 16 | 68 | 159 | 3 | 0 | 0 | 0 | 18 | 7 | 3 | 3.58 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 28 | 28 | 9 | 13 | 4.32 | .295 | 1.24 | 8.7 | 2.5 | 3.6 | 195.2 | 188 | 104 | 94 | 15 | 54 | 78 | 8 | 0 | 0 | 3 | 14 | 4 | 5 | 4.09 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 27 | 27 | 10 | 10 | 4.50 | .309 | 1.32 | 8.8 | 3.1 | 7.9 | 180.0 | 176 | 90 | 90 | 23 | 61 | 158 | 4 | 0 | 0 | 1 | 13 | 4 | 6 | 3.99 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 63 | 0 | 8 | 3 | 4.46 | .303 | 1.30 | 8.0 | 3.9 | 8.5 | 70.2 | 62 | 38 | 35 | 10 | 30 | 66 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.26 |
| SU | Davis, W.Davis, Wade # >> | 29 | 2015 | R | 89 | 48 | 0 | 1 | 0 | 5.44 | .350 | 1.61 | 9.8 | 4.9 | 8.2 | 44.2 | 48 | 27 | 27 | 7 | 24 | 40 | 0 | 3 | 7 | 0 | 0 | 0 | 0 | 4.89 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 99 | 53 | 0 | 5 | 4 | 2.29 | .292 | 1.24 | 6.5 | 4.6 | 8.7 | 55.0 | 40 | 15 | 14 | 1 | 28 | 53 | 0 | 28 | 5 | 0 | 0 | 0 | 0 | 2.84 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 35 | 0 | 2 | 1 | 4.10 | .329 | 1.42 | 10.5 | 2.4 | 8.5 | 37.1 | 43 | 20 | 17 | 3 | 10 | 35 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.14 |