| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 29 | 29 | 16 | 6 | 3.04 | .261 | 1.04 | 7.2 | 2.2 | 9.5 | 201.0 | 161 | 69 | 68 | 19 | 49 | 212 | 2 | 0 | 0 | 1 | 19 | 3 | 0 | 2.90 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 28 | 28 | 10 | 11 | 4.47 | .299 | 1.27 | 8.8 | 2.6 | 8.4 | 179.1 | 176 | 101 | 89 | 30 | 51 | 167 | 1 | 0 | 0 | 0 | 15 | 2 | 3 | 4.20 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 27 | 27 | 11 | 8 | 4.28 | .323 | 1.39 | 8.9 | 3.6 | 4.6 | 168.1 | 167 | 91 | 80 | 10 | 67 | 86 | 2 | 0 | 0 | 1 | 11 | 7 | 1 | 4.07 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 26 | 26 | 12 | 10 | 4.68 | .291 | 1.22 | 9.1 | 1.9 | 5.8 | 178.2 | 180 | 97 | 93 | 31 | 38 | 114 | 11 | 0 | 0 | 2 | 11 | 2 | 1 | 4.66 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 70 | 0 | 4 | 4 | 3.09 | .322 | 1.42 | 8.1 | 4.8 | 9.3 | 58.1 | 52 | 25 | 20 | 8 | 31 | 60 | 0 | 7 | 3 | 0 | 0 | 0 | 3 | 4.33 |
| RP | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 93 | 56 | 0 | 1 | 3 | 3.59 | .301 | 1.24 | 7.3 | 4.1 | 7.9 | 42.2 | 34 | 18 | 17 | 7 | 19 | 37 | 0 | 8 | 1 | 0 | 0 | 2 | 0 | 4.90 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 31 | 0 | 2 | 5 | 5.46 | .344 | 1.50 | 9.6 | 3.9 | 6.4 | 28.0 | 30 | 17 | 17 | 6 | 12 | 20 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 5.86 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 16 | 0 | 0 | 1 | 2.84 | .309 | 1.34 | 9.8 | 3.0 | 10.5 | 12.2 | 13 | 4 | 4 | 0 | 4 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.67 |