| SP | Cortes Jr., N.Cortes Jr., Nestor >> | 27 | 2022 | L | 97 | 28 | 28 | 11 | 10 | 4.19 | .311 | 1.33 | 8.2 | 3.8 | 8.8 | 156.2 | 142 | 73 | 73 | 21 | 66 | 153 | 0 | 0 | 0 | 0 | 14 | 4 | 2 | 4.13 |
| SP | Severino, L.Severino, Luis >> | 28 | 2022 | R | 93 | 27 | 27 | 9 | 5 | 4.76 | .325 | 1.42 | 9.4 | 3.4 | 9.4 | 138.0 | 144 | 76 | 73 | 18 | 52 | 144 | 0 | 0 | 0 | 0 | 10 | 3 | 0 | 3.80 |
| SP | Rodon, C.Rodon, Carlos >> | 32 | 2025 | L | 89 | 27 | 27 | 12 | 9 | 4.31 | .332 | 1.48 | 8.8 | 4.6 | 9.7 | 152.1 | 149 | 74 | 73 | 15 | 77 | 163 | 0 | 0 | 0 | 0 | 13 | 1 | 4 | 3.68 |
| SP | Cole, G.Cole, Gerrit # >> | 31 | 2022 | R | 87 | 26 | 26 | 18 | 4 | 4.34 | .310 | 1.32 | 8.8 | 3.1 | 11.0 | 161.2 | 158 | 78 | 78 | 32 | 56 | 196 | 0 | 0 | 0 | 0 | 13 | 4 | 1 | 4.27 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 63 | 26 | 26 | 6 | 5 | 6.37 | .358 | 1.65 | 11.5 | 3.4 | 7.4 | 148.1 | 189 | 108 | 105 | 20 | 56 | 122 | 0 | 0 | 0 | 0 | 9 | 3 | 5 | 4.30 |
| RP | Marinaccio, R.Marinaccio, Ron # >> | 26 | 2022 | R | 83 | 75 | 0 | 5 | 4 | 4.44 | .319 | 1.41 | 6.7 | 6.0 | 7.8 | 97.1 | 72 | 48 | 48 | 9 | 65 | 84 | 0 | 0 | 1 | 0 | 0 | 0 | 13 | 4.48 |
| CL | Rivera, M.Rivera, Mariano † >> | 32 | 2001 | R | 77 | 56 | 0 | 4 | 4 | 3.54 | .280 | 1.13 | 7.8 | 2.4 | 7.7 | 61.0 | 53 | 25 | 24 | 8 | 16 | 52 | 0 | 31 | 5 | 0 | 0 | 2 | 1 | 3.89 |
| RP | Weaver, L.Weaver, Luke >> | 31 | 2025 | R | 73 | 60 | 0 | 7 | 3 | 4.39 | .309 | 1.34 | 6.6 | 5.5 | 9.7 | 65.2 | 48 | 32 | 32 | 7 | 40 | 70 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 4.09 |
| RP | Holmes, C.Holmes, Clay >> | 29 | 2022 | R | 72 | 40 | 0 | 0 | 2 | 2.68 | .322 | 1.40 | 8.8 | 3.8 | 7.5 | 47.0 | 46 | 14 | 14 | 2 | 20 | 39 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 3.23 |
| RP | Williams, D.Williams, Devin >> | 30 | 2025 | R | 58 | 34 | 0 | 2 | 2 | 3.35 | .335 | 1.51 | 8.0 | 5.8 | 11.9 | 37.2 | 33 | 14 | 14 | 2 | 24 | 49 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.00 |
| RP | Chapman, A.Chapman, Aroldis >> | 34 | 2022 | L | 44 | 37 | 0 | 1 | 3 | 6.89 | .420 | 2.14 | 11.3 | 8.4 | 9.0 | 32.2 | 40 | 25 | 25 | 5 | 30 | 32 | 0 | 0 | 4 | 0 | 0 | 1 | 9 | 5.94 |