| SP | Martinez, P.Martinez, Pedro # >> | 28 | 1999 | R | 95 | 28 | 28 | 15 | 8 | 3.52 | .275 | 1.11 | 7.7 | 2.4 | 10.9 | 174.0 | 148 | 73 | 68 | 23 | 46 | 211 | 4 | 0 | 0 | 1 | 16 | 4 | 4 | 3.16 |
| SP | Clemens, R.Clemens, Roger # >> | 34 | 1996 | R | 28 | 27 | 27 | 6 | 14 | 5.47 | .357 | 1.64 | 10.3 | 4.4 | 9.2 | 148.0 | 170 | 96 | 90 | 28 | 73 | 151 | 0 | 0 | 0 | 0 | 12 | 3 | 3 | 4.96 |
| SP | Schilling, C.Schilling, Curt # >> | 41 | 2007 | R | 18 | 27 | 27 | 8 | 14 | 6.89 | .368 | 1.73 | 12.9 | 2.7 | 6.1 | 146.1 | 210 | 126 | 112 | 31 | 43 | 99 | 0 | 0 | 0 | 0 | 10 | 3 | 0 | 5.35 |
| SP | Wakefield, T.Wakefield, Tim >> | 41 | 2007 | R | 12 | 24 | 23 | 6 | 6 | 5.68 | .352 | 1.60 | 10.2 | 4.2 | 6.3 | 139.1 | 158 | 97 | 88 | 17 | 65 | 98 | 2 | 0 | 0 | 0 | 7 | 4 | 7 | 4.67 |
| RP | Timlin, M.Timlin, Mike >> | 41 | 2007 | R | 49 | 67 | 0 | 4 | 2 | 3.96 | .304 | 1.29 | 8.9 | 2.7 | 5.0 | 84.0 | 83 | 38 | 37 | 17 | 25 | 47 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 5.48 |
| RP | Garces, R.Garces, Rich >> | 28 | 1999 | R | 68 | 62 | 0 | 7 | 3 | 4.92 | .343 | 1.54 | 9.4 | 4.5 | 6.3 | 82.1 | 86 | 45 | 45 | 7 | 41 | 57 | 0 | 0 | 4 | 0 | 0 | 2 | 0 | 4.29 |
| RP | Delcarmen, M.Delcarmen, Manny >> | 25 | 2007 | R | 78 | 43 | 0 | 2 | 0 | 3.91 | .332 | 1.47 | 8.8 | 4.5 | 7.5 | 48.1 | 47 | 22 | 21 | 9 | 24 | 40 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 5.33 |
| SU | Okajima, H.Okajima, Hideki >> | 32 | 2007 | L | 76 | 58 | 0 | 3 | 0 | 3.33 | .258 | 0.99 | 5.8 | 3.1 | 8.8 | 73.0 | 47 | 28 | 27 | 8 | 25 | 71 | 0 | 4 | 4 | 0 | 0 | 4 | 0 | 3.67 |
| CL | Papelbon, J.Papelbon, Jonathan † >> | 27 | 2007 | R | 99 | 54 | 0 | 4 | 5 | 2.54 | .258 | 1.04 | 6.6 | 2.9 | 9.5 | 60.1 | 44 | 17 | 17 | 5 | 19 | 63 | 0 | 27 | 1 | 0 | 0 | 0 | 0 | 2.93 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 42 | 14 | 4 | 2 | 4 | 8.03 | .400 | 1.92 | 14.4 | 2.9 | 6.3 | 37.0 | 59 | 33 | 33 | 7 | 12 | 26 | 0 | 0 | 0 | 0 | 1 | 3 | 3 | 5.27 |