| SP | Verlander, J.Verlander, Justin >> | 28 | 2011 | R | 97 | 12 | 12 | 8 | 0 | 2.83 | .279 | 1.16 | 7.6 | 2.8 | 7.2 | 86.0 | 73 | 27 | 27 | 5 | 27 | 69 | 2 | 0 | 0 | 1 | 9 | 0 | 1 | 3.09 |
| SP | Skubal, T.Skubal, Tarik # >> | 28 | 2025 | L | 98 | 12 | 12 | 7 | 2 | 3.63 | .274 | 1.13 | 8.4 | 1.8 | 10.8 | 79.1 | 74 | 33 | 32 | 11 | 16 | 95 | 0 | 0 | 0 | 0 | 7 | 0 | 1 | 3.01 |
| SP | Scherzer, M.Scherzer, Max >> | 29 | 2013 | R | 94 | 12 | 12 | 4 | 5 | 4.12 | .332 | 1.48 | 10.4 | 2.9 | 8.2 | 83.0 | 96 | 43 | 38 | 11 | 27 | 76 | 0 | 0 | 0 | 0 | 6 | 1 | 1 | 3.90 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 90 | 12 | 12 | 4 | 6 | 4.63 | .309 | 1.31 | 8.9 | 3.0 | 6.7 | 83.2 | 82 | 45 | 43 | 13 | 28 | 62 | 5 | 0 | 0 | 1 | 5 | 2 | 2 | 4.63 |
| SP | Hiller, J.Hiller, John >> | 25 | 1968 | L | 72 | 4 | 4 | 0 | 0 | 3.68 | .323 | 1.43 | 9.6 | 3.9 | 5.8 | 14.2 | 15 | 6 | 6 | 2 | 6 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.86 |
| CL | Benoit, J.Benoit, Joaquin >> | 36 | 2013 | R | 77 | 22 | 0 | 1 | 2 | 3.42 | .336 | 1.48 | 10.6 | 3.1 | 10.2 | 23.2 | 27 | 9 | 9 | 5 | 8 | 26 | 0 | 15 | 2 | 0 | 0 | 1 | 0 | 4.74 |
| SU | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 74 | 24 | 0 | 2 | 1 | 2.97 | .326 | 1.38 | 8.7 | 3.9 | 6.3 | 30.1 | 29 | 12 | 10 | 3 | 13 | 21 | 0 | 4 | 4 | 0 | 0 | 2 | 1 | 4.40 |
| RP | Alburquerque, A.Alburquerque, Al >> | 25 | 2011 | R | 70 | 33 | 0 | 1 | 1 | 4.70 | .330 | 1.39 | 7.8 | 4.7 | 10.2 | 23.0 | 20 | 12 | 12 | 4 | 12 | 26 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 4.83 |
| RP | Holton, T.Holton, Tyler >> | 29 | 2025 | L | 49 | 16 | 0 | 0 | 2 | 9.00 | .382 | 1.86 | 15.4 | 1.3 | 5.1 | 7.0 | 12 | 7 | 7 | 3 | 1 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.86 |
| SP | Lolich, M.Lolich, Mickey >> | 28 | 1968 | L | 68 | 9 | 8 | 1 | 3 | 5.62 | .321 | 1.37 | 9.0 | 3.5 | 9.0 | 41.2 | 41 | 26 | 26 | 8 | 16 | 41 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 4.85 |
| SP | Fister, D.Fister, Doug >> | 27 | 2011 | R | 57 | 8 | 0 | 1 | 1 | 4.99 | .313 | 1.27 | 10.2 | 1.5 | 5.1 | 30.2 | 34 | 18 | 17 | 3 | 5 | 17 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 3.97 |