| SP | Kershaw, C.Kershaw, Clayton † >> | 27 | 2015 | L | 92 | 34 | 34 | 23 | 6 | 3.01 | .282 | 1.13 | 8.2 | 1.9 | 9.8 | 251.0 | 230 | 89 | 84 | 19 | 54 | 274 | 6 | 0 | 0 | 1 | 23 | 12 | 3 | 2.59 |
| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 96 | 33 | 33 | 20 | 5 | 2.99 | .285 | 1.18 | 8.1 | 2.6 | 7.5 | 237.2 | 213 | 84 | 79 | 19 | 68 | 198 | 8 | 0 | 0 | 2 | 23 | 3 | 11 | 3.27 |
| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 100 | 32 | 32 | 15 | 10 | 3.98 | .286 | 1.18 | 7.7 | 3.0 | 10.1 | 194.1 | 165 | 97 | 86 | 24 | 65 | 218 | 0 | 0 | 0 | 0 | 17 | 4 | 5 | 3.43 |
| SP | Buehler, W.Buehler, Walker >> | 26 | 2021 | R | 81 | 32 | 32 | 15 | 9 | 4.57 | .315 | 1.35 | 9.0 | 3.2 | 9.0 | 200.2 | 199 | 108 | 102 | 22 | 72 | 201 | 0 | 0 | 0 | 0 | 18 | 6 | 5 | 3.59 |
| SP | Bauer, T.Bauer, Trevor † >> | 30 | 2021 | R | 83 | 31 | 31 | 15 | 4 | 3.81 | .317 | 1.39 | 8.4 | 4.1 | 9.5 | 165.1 | 154 | 71 | 70 | 18 | 75 | 174 | 0 | 0 | 0 | 0 | 6 | 1 | 3 | 3.69 |
| CL | Jansen, K.Jansen, Kenley † >> | 27 | 2015 | R | 98 | 61 | 0 | 2 | 6 | 3.56 | .268 | 1.08 | 7.7 | 2.1 | 10.6 | 55.2 | 47 | 22 | 22 | 7 | 13 | 65 | 0 | 44 | 4 | 0 | 0 | 1 | 0 | 3.05 |
| RP | Treinen, B.Treinen, Blake # >> | 33 | 2021 | R | 83 | 81 | 0 | 2 | 1 | 4.93 | .331 | 1.47 | 7.6 | 5.7 | 9.4 | 69.1 | 58 | 41 | 38 | 7 | 44 | 72 | 0 | 3 | 3 | 0 | 0 | 1 | 1 | 4.19 |
| RP | Bickford, P.Bickford, Phil >> | 25 | 2021 | R | 69 | 17 | 0 | 1 | 1 | 8.04 | .397 | 1.98 | 14.4 | 4.2 | 7.2 | 15.2 | 24 | 16 | 14 | 6 | 7 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.00 |