| SP | Johnson, R.Johnson, Randy # >> | 38 | 2001 | L | 97 | 15 | 15 | 7 | 6 | 2.85 | .244 | 0.91 | 6.2 | 2.1 | 9.6 | 117.0 | 80 | 37 | 37 | 16 | 27 | 125 | 3 | 0 | 0 | 0 | 11 | 6 | 3 | 3.49 |
| SP | Loaiza, E.Loaiza, Esteban >> | 32 | 2003 | R | 60 | 15 | 15 | 6 | 7 | 5.50 | .341 | 1.55 | 10.9 | 3.1 | 7.5 | 88.1 | 107 | 59 | 54 | 17 | 30 | 73 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 4.88 |
| SP | Clement, M.Clement, Matt >> | 28 | 2002 | R | 54 | 15 | 15 | 5 | 8 | 4.63 | .325 | 1.40 | 8.4 | 4.3 | 8.5 | 93.1 | 87 | 49 | 48 | 11 | 44 | 88 | 1 | 0 | 0 | 1 | 7 | 4 | 6 | 4.19 |
| SP | Harang, A.Harang, Aaron >> | 29 | 2007 | R | 51 | 15 | 15 | 7 | 2 | 3.60 | .325 | 1.42 | 9.4 | 3.4 | 6.8 | 90.0 | 94 | 36 | 36 | 9 | 34 | 68 | 0 | 0 | 0 | 0 | 9 | 2 | 4 | 3.99 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 56 | 30 | 0 | 3 | 4 | 4.37 | .286 | 1.14 | 5.7 | 4.6 | 7.7 | 35.0 | 22 | 17 | 17 | 6 | 18 | 30 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 5.23 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 40 | 20 | 0 | 2 | 1 | 4.03 | .295 | 1.25 | 9.8 | 1.6 | 8.6 | 22.1 | 24 | 10 | 10 | 7 | 4 | 21 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.77 |
| SP | Miller, W.Miller, Wade >> | 25 | 2001 | R | 29 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Kazmir, S.Kazmir, Scott >> | 24 | 2008 | L | 40 | 9 | 0 | 1 | 1 | 5.87 | .352 | 1.57 | 8.4 | 6.0 | 10.8 | 15.1 | 14 | 10 | 10 | 4 | 10 | 18 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 6.27 |