| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 15 | 15 | 1 | 3 | 3.53 | .302 | 1.25 | 8.3 | 3.0 | 8.3 | 66.1 | 61 | 26 | 26 | 12 | 22 | 61 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 4.65 |
| SP | Maddux, G.Maddux, Greg # >> | 34 | 2000 | R | 58 | 15 | 15 | 6 | 2 | 4.51 | .300 | 1.25 | 9.9 | 1.4 | 4.7 | 101.2 | 111 | 53 | 51 | 18 | 16 | 53 | 5 | 0 | 0 | 1 | 7 | 4 | 1 | 4.86 |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 47 | 15 | 15 | 5 | 6 | 7.19 | .384 | 1.87 | 12.8 | 4.1 | 7.4 | 81.1 | 115 | 67 | 65 | 16 | 37 | 67 | 0 | 0 | 0 | 0 | 3 | 0 | 2 | 5.28 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 39 | 0 | 2 | 3 | 6.26 | .311 | 1.32 | 7.7 | 4.3 | 8.2 | 54.2 | 46 | 38 | 38 | 10 | 26 | 49 | 0 | 3 | 4 | 0 | 0 | 2 | 1 | 5.15 |
| RP | Linebrink, S.Linebrink, Scott >> | 28 | 2004 | R | 45 | 28 | 0 | 0 | 0 | 6.32 | .369 | 1.72 | 13.1 | 2.6 | 6.4 | 31.1 | 45 | 22 | 22 | 5 | 9 | 22 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 4.65 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 34 | 26 | 0 | 3 | 0 | 6.04 | .331 | 1.45 | 7.1 | 6.1 | 9.3 | 28.1 | 22 | 19 | 19 | 4 | 19 | 29 | 0 | 3 | 0 | 0 | 0 | 1 | 2 | 4.93 |