| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 15 | 15 | 2 | 5 | 3.88 | .303 | 1.26 | 7.7 | 3.8 | 8.7 | 67.1 | 57 | 29 | 29 | 7 | 28 | 65 | 0 | 0 | 0 | 0 | 1 | 3 | 3 | 3.81 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 88 | 15 | 15 | 7 | 7 | 5.44 | .326 | 1.43 | 9.7 | 3.2 | 8.7 | 99.1 | 107 | 60 | 60 | 13 | 35 | 96 | 1 | 0 | 0 | 0 | 7 | 2 | 2 | 3.89 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 15 | 15 | 3 | 7 | 8.84 | .391 | 1.88 | 13.2 | 3.8 | 6.9 | 73.1 | 107 | 72 | 72 | 20 | 31 | 56 | 0 | 0 | 0 | 0 | 3 | 3 | 1 | 6.42 |
| SP | Maddux, G.Maddux, Greg # >> | 34 | 2000 | R | 58 | 14 | 14 | 7 | 3 | 3.61 | .308 | 1.32 | 9.7 | 2.3 | 5.9 | 107.1 | 115 | 44 | 43 | 12 | 27 | 70 | 2 | 0 | 0 | 0 | 8 | 1 | 1 | 3.93 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 87 | 39 | 0 | 2 | 1 | 2.80 | .211 | 0.80 | 5.0 | 2.2 | 6.0 | 45.0 | 25 | 14 | 14 | 4 | 11 | 30 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 3.56 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 75 | 39 | 0 | 1 | 0 | 3.29 | .281 | 1.13 | 8.3 | 2.0 | 10.3 | 27.1 | 25 | 10 | 10 | 3 | 6 | 31 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 2.93 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 68 | 22 | 0 | 3 | 0 | 2.33 | .283 | 1.15 | 6.7 | 3.7 | 6.0 | 27.0 | 20 | 7 | 7 | 1 | 11 | 18 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.48 |