| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 15 | 15 | 8 | 4 | 3.28 | .285 | 1.17 | 8.3 | 2.2 | 10.6 | 109.2 | 101 | 41 | 40 | 11 | 27 | 128 | 1 | 0 | 0 | 0 | 11 | 3 | 0 | 2.79 |
| SP | Peavy, J.Peavy, Jake # >> | 26 | 2007 | R | 89 | 15 | 15 | 10 | 2 | 2.92 | .269 | 1.06 | 6.7 | 2.9 | 9.4 | 101.2 | 75 | 34 | 33 | 9 | 33 | 106 | 0 | 0 | 0 | 0 | 12 | 4 | 1 | 3.16 |
| SP | Williams, W.Williams, Woody >> | 36 | 2002 | R | 79 | 15 | 15 | 5 | 4 | 5.03 | .318 | 1.35 | 8.9 | 3.3 | 6.6 | 91.1 | 90 | 51 | 51 | 15 | 33 | 67 | 0 | 0 | 0 | 0 | 8 | 5 | 1 | 4.92 |
| SP | Millwood, K.Millwood, Kevin >> | 28 | 2002 | R | 51 | 15 | 15 | 8 | 5 | 4.97 | .340 | 1.52 | 10.5 | 3.3 | 7.6 | 88.2 | 103 | 52 | 49 | 16 | 32 | 74 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 4.84 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 86 | 45 | 0 | 6 | 1 | 1.46 | .260 | 1.03 | 7.7 | 1.7 | 9.2 | 49.1 | 42 | 8 | 8 | 1 | 9 | 50 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1.84 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 77 | 25 | 0 | 1 | 0 | 1.93 | .176 | 0.61 | 4.8 | 0.6 | 9.3 | 28.0 | 15 | 9 | 6 | 3 | 2 | 29 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.64 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 69 | 15 | 0 | 0 | 1 | 7.56 | .367 | 1.68 | 11.3 | 4.5 | 9.0 | 16.2 | 20 | 16 | 14 | 4 | 8 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5.94 |
| SU | Wagner, B.Wagner, Billy >> | 32 | 2003 | L | 89 | 23 | 0 | 2 | 0 | 2.45 | .214 | 0.77 | 4.9 | 2.0 | 7.8 | 22.0 | 12 | 6 | 6 | 2 | 5 | 19 | 0 | 0 | 4 | 0 | 0 | 1 | 1 | 3.27 |